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Treat Yo Self (Team 14) - Magnesium for Asthma
Top 5 things a pharmacist should let patients know: 1. Magnesium can cause toxic effects in people taking certain blood pressure medications, or affect minerals like fluoride, phosphate supplements or levothyroxine. 2. Further studies need to be done for proof, but magnesium may help with asthmatic symptoms. This is more commonly used to treat constipation or low magnesium levels in the body. 3. How it works: Magnesium prevents your muscle cells from taking in calcium, and it's the calcium that makes the muscle in your lungs tighten up. So, your lungs will relax and help you breathe better. 4. Some common side effects you may experience are diarrhea, nausea, or vomiting. It's always important to stay hydrated. 5. Contraindications include: Don't take magnesium if you have kidney or heart disease, or if you are pregnant. References: Natural Medicines. Food, Herbs, & Supplements. Magnesium. Available at: https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=998. Accessed September 10th, 2017. DRUGDEX® System (electronic version). Truven Health Analytics, Greenwood Village, Colorado, USA. Available at: http://www.micromedexsolutions.com/micromedex2/librarian/PFDefaultActionId/evidencexpert.DoIntegratedSearch# (cited: 9/12/2017). Kokotajlo S, Degnan L, Meyers R, Siu A, Robinson C. Use of Intravenous Magnesium Sulfate for the Treatment of an Acute Asthma Exacerbation in Pediatric Patients. The Journal of Pediatric Pharmacology and Therapeutics : JPPT. 2014;19(2):91-97. doi:10.5863/1551-6776-19.2.91. Rowe BH, Bretzlaff JA, Bourdon C, et al: Intravenous magnesium sulfate treatment for acute asthma in the emergency department: a systematic review of the literature. Ann Emerg Med 2000; 36(3):181-190. Kazaks AG, Uriu-Adams JY, Albertson TE, Shenoy SF, Stern JS. Effect of oral magnesium supplementation on measures of airway resistance and subjective assessment of asthma control and quality of life in men and women with mild to moderate asthma: a randomized placebo controlled trial. J Asthma. 2010 Feb;47:83-92. Bichara, Marcel Davalos, Goldman, Ran D. MD. Magnesium for treatment of asthma in children. Can Fam Physician. 2009; 55(9): 887-889. Lexicomp OnlineⓇ, Lexi-DrugsⓇ, Hudson, Ohio: Lexi-Comp, Inc.; September 15, 2017. https://online.lexi.com/lco/action/doc/retrieve/docid/patch_f/7216#f_interactions
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Team 1: MSM and Chondroitin for Osteoarthritis 2017
Top 5 Things a Pharmacist Should Know to Tell Patients: 1. Methylsulfonylmethane (MSM) and Chondroitin are used for osteoarthritis to reduce inflammation and ease pain. 2. MSM and chondroitin are often found in combination with glucosamine, which should not be taken by patients with a shellfish allergy. 3. Avoid use if you are taking “blood thinning” drugs like warfarin, or if you are at a high risk of bleeding. 4. Side effects include stomach upset, headaches, and difficulty sleeping. 5. Dosing: 1,200mg of chondroitin and 1,500 to 3,000mg of MSM taken by mouth with food daily in 1 or divided doses. References: 1. Lexicomp Online, Natural Products Database, Hudson, Ohio: Wolters Kluwer Clinical Drug Information, Inc.; 2017, September 12, 2017. 2. Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006;14:286-94. Epub 2005 Nov 23. 3. Lubis AMT, Siagian C, Wonggokusuma E, Marsetyo AF, Setyohadi B. Comparison of Glucosamine-Chondroitin Sulfate with and without Methylsulfonylmethane in Grade I-II Knee Osteoarthritis: A Double Blind Randomized Controlled Trial. Acta Med Indones. 2017; 49:105-111. 4. (Chondroitin). In: AltMedDex® System (electronic version). Truven Health Analytics, Greenwood Village, Colorado, USA. Available at: http://www.micromedexsolutions.com/ (cited: September/14/2017). 5. McQueen CE, Orr KK.  Chapter 51: Natural Products In: Krinsky DL, Perreri SP, Hemstreet B, Hume AL, Newton GD, Rollins CJ, Tietze KJ,editors. Handbook of nonprescription drugs: An interactive approach to self-care. 18th ed. Washington: American Pharmacists Association; 2015. Available at: http://pharmacylibrary.com.uri.idm.oclc.org/doi/full/10.21019/9781582122250.ch5. Accessed September 15, 2017.
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