Quetiapine is a second-generation (atypical) antipsychotic. It’s approved by the FDA for schizophrenia, acute bipolar mania/mixed and depression, and bipolar maintenance (as an add-on to lithium or divalproex). The extended-release form is also approved as an add-on for depression.
Though its approved uses are limited, it’s widely used off-label as a single therapy for depression, anxiety, insomnia, OCD, and other conditions.
TDC overview page (with references): https://thedrugclassroom.com/video/quetiapine/
Reddit discussion: https://www.reddit.com/r/TheDrugClassroom/comments/7de3mv/quetiapine_seroquel_what_you_need_to_know/
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00:17 - Effects
06:09 - Chemistry & Pharmacology
10:50 - How It's Used
11:15 - History
13:17 - Legality
13:33 - Safety
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