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Lung Cancer Progression And Staging - Manipal Hospitals
 
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The most common form of lung cancer is non-small cell lung cancer. It is staged according to the size of the tumour and whether it has spread to the lymph nodes or other organs of the body. There are 4 stages of lung cancer. In the occult stage, cancer cells are accumulated in the fluids in the lungs and there is no tumour yet. In stage 0, cancer cells are found in the airway passages. Stage 1A and 1B are invasive cancer as tumour grows in the inner lining of airways and then spread into the bronchus. In stage 2A, it spreads to the lymph nodes on the same side of the chest. Stage 2B has two categories in which the cancer has invaded the diaphragm, chest walls and membranes around the heart and the tumour has grown in the bronchus and lymph nodes. In stage 3A, it spreads to lymph nodes and other structures nearby. In 3B, tumour may be of any size and spread to more lymph nodes on the same side and to nearby structures too. In stage 4, tumour has spread in other parts of the body. This informative animated video explains in detail about the staging and progression of lung cancer. The staging of lung cancer refers to the extent of the disease. If one has the most common form of lung cancer or non-small cell lung cancer, it will be staged according to the size of the tumour and whether it has spread to lymph nodes or other nodes of the body. In occult or hidden stage, the cancer cells are found in the coughed up mucus or in other fluids, but no tumour can be seen in the lungs. Stage zero is not considered invasive because the cancer cells are found in the innermost lining of the air passages, but have not grown through it. Stage 1A is known as the invasive cancer, because the tumour has grown the inner lining of the airways into the deep lung tissue. Watch the video completely to know more on the staging of lung cancer. Manipal Hospitals is a certified pioneer in the Indian health-care industry for over 6 decades and has been delivering top-notch health-care services that are curative, preventive and rehabilitative. In an effort to increase awareness on heath concerns among the general public, world-class animation videos are presented in this channel. To know more visit our website : https://www.manipalhospitals.com/ Get Connected Here: ================== Facebook: https://www.facebook.com/ManipalHospitalsIndia Google+: https://plus.google.com/111550660990613118698 Twitter: https://twitter.com/ManipalHealth Pinterest: https://in.pinterest.com/manipalhospital Linkedin: https://www.linkedin.com/company/manipal-hospital Instagram: https://www.instagram.com/manipalhospitals/ Foursquare: https://foursquare.com/manipalhealth Alexa: http://www.alexa.com/siteinfo/manipalhospitals.com Blog: https://www.manipalhospitals.com/blog/
Просмотров: 10395 Manipal Hospitals
Lung Cancer Staging Explained Clearly by MedCram.com
 
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Dr. Roger Seheult of http://www.medcram.com with an easy to follow overview of lung cancer staging and lung cancer treatment. Includes an overview of staging and treatment for non small cell lung cancers (NSCLC): squamous cell lung cancer, adenocarcinoma, and large cell carcinoma. Staging and treatment for small cell lung cancer (SCLC, oat cell carcinoma) is also covered. Tumor node metastasis (TNM) staging system is discussed in detail. This is part 1 of lung cancer staging and treatment. Visit http://www.medcram.com for this entire course and over 100 free lectures. This is the home for ALL MedCram.com medical videos (many medical videos, medical lectures, and quizzes are not on YouTube). Speaker: Roger Seheult, MD Co-Founder of MedCram.com (https://www.medcram.com) Clinical and Exam Preparation Instructor Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine. MedCram: Medical education topics explained clearly including: Respiratory lectures such as Asthma and COPD. Renal lectures on Acute Renal Failure and Adrenal Gland. Internal medicine videos on Oxygen Hemoglobin Dissociation Curve and Medical Acid Base. A growing library on critical care topics such as Shock, Diabetic Ketoacidosis (DKA), and Mechanical Ventilation. Cardiology videos on Hypertension and heart failure. VQ Mismatch and Hyponatremia lectures have been popular among medical students. Our Pulmonary Function Tests (PFTs) videos have been particularly popular with RTs. NPs and PAs have given great feedback on Pneumonia Treatment and Liver Function Tests among many others. Many nursing students have found the Asthma and shock lectures very helpful. New free medical education videos are released first at MedCram.com Visit MedCram.com for the full library of MedCram medical videos: https://www.medcram.com Subscribe to the official MedCram.com YouTube Channel: https://www.youtube.com/subscription_center?add_user=medcramvideos Recommended Audience - Health care professionals and medical students: including physicians, nurse practitioners, physician assistants, nurses, respiratory therapists, EMT and paramedics, and many others. Review and test prep for USMLE, MCAT, PANCE, NCLEX, NAPLEX, NBDE, RN, RT, MD, DO, PA, NP school and board examinations. More from MedCram.com medical videos: MedCram Website: https://www.medcram.com Facebook: https://www.facebook.com/MedCram Google+: https://plus.google.com/u/1/+Medcram Twitter: https://twitter.com/MedCramVideos Produced by Kyle Allred PA-C Please note: MedCram medical videos, medical lectures, medical illustrations, and medical animations are for medical educational and exam preparation purposes, and not intended to replace recommendations by your doctor or health care provider.
Просмотров: 10930 MedCram - Medical Lectures Explained CLEARLY
Brigatinib at Disease Progression of ALK-Rearranged NSCLC
 
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Corey J. Langer, MD, discusses the rationale for using brigatinib in a patient with progression of ALK-translocated non–small cell lung cancer and the data on which the drug was approved and provides important information about dosing and management of potential pulmonary toxicity. For more resources and information regarding anticancer targeted therapies: http://targetedonc.com/
Просмотров: 139 Targeted Oncology
Lung Cancer Facts : Last Signs of Lung Cancer Before Death
 
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The last signs of lung cancer before death include being unable to perform simple tasks independently, having difficulty breathing and experiencing intense chest pain. Discover the options to ease these final symptoms with helpful information from a practicing oncologist in this free video on cancer. Expert: Dr. Kenneth Fink Contact: www.nhhn.org Bio: Dr. Kenneth Fink has been a medical doctor in the field of internal medicine specializing in hematology and oncology for 23 years. Filmmaker: Reel Media LLC
Просмотров: 251514 eHow
Improving Survival in Lung Cancer
 
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Most patients with stage III, locally advanced, unresectable non–small-cell lung cancer have disease progression despite chemotherapy with concurrent radiation. New research findings are summarized in this short video. Full study: http://nej.md/2wK3KNL Watch more Quick Take videos: http://nej.md/quick-take
Просмотров: 1578 NEJMvideo
Managing Disease Progression in Advanced NSCLC
 
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Corey J. Langer, MD, discusses brain metastases in patients with EGFR-mutant non–small cell lung cancer, remarks on concerns for resistance to EGFR–tyrosine kinase inhibitor therapy, and highlights considerations for monitoring and managing patients following disease progression. For more resources and information regarding anticancer targeted therapies: http://targetedonc.com/
Просмотров: 17 Targeted Oncology
Lung cancer staging | Respiratory system diseases | NCLEX-RN | Khan Academy
 
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Health professionals use special terminology referred to as stages to concisely communicate the progression of cancer disease. Learn how cancer is classified based off the size of the tumor, the involvement of lymph nodes, and whether metastasis has occurred. Created by Amanda Grieco. Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/rn-respiratory-system-diseases/rn-lung-cancer/v/lung-cancer-treatment?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn Missed the previous lesson? https://www.khanacademy.org/test-prep/nclex-rn/rn-respiratory-system-diseases/rn-lung-cancer/v/lung-cancer-metastasis?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn NCLEX-RN on Khan Academy: A collection of questions from content covered on the NCLEX-RN. These questions are available under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States License (available at http://creativecommons.org/licenses/by-nc-sa/3.0/us/). About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s NCLEX-RN channel: https://www.youtube.com/channel/UCDx5cTeADCvKWgF9x_Qjz3g?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
Просмотров: 28818 khanacademymedicine
Defining Progression of NSCLC on Immunotherapy
 
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Corey Langer, MD, discusses progressive disease in a patient receiving immunotherapy, distinguishing between pseudoprogression and real progression in non–small cell lung cancer. For more resources and information regarding anticancer targeted therapies: http://targetedonc.com/
Просмотров: 106 Targeted Oncology
Types And Staging Of Lung Cancer - Manipal Hospitals
 
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Lungs cancer is of two types; Small cell lungs cancer and non-small cell lungs cancer. In limited stage small cell lung cancer, cancer cells are found in one lung and the nearby lymph node. In extensive stage, cancer cells spread to the other lung, lymph nodes and even to the other part of the body. This informative animated video explains in detail about the staging and progression of lung cancer. The staging of lung cancer refers to the extent of the disease. If one has small cell lung cancer, it is often staged by simpler two part system because treatment options don’t vary much between the more detailed stages used to describe non-small cell lung cancer. In limited stage small cell lung cancer, cancer cells are found in one lung and may be found in the tissues between the lungs and in nearby lymph nodes. If cancer is found in the other lung in the lymph nodes on other side of the chest point other parts of the body it is called extensive stage. Manipal Hospitals is a certified pioneer in the Indian health-care industry for over 6 decades and has been delivering top-notch health-care services that are curative, preventive and rehabilitative. In an effort to increase awareness on heath concerns among the general public, world-class animation videos are presented in this channel. To know more visit our website : https://www.manipalhospitals.com/ Get Connected Here: ================== Facebook: https://www.facebook.com/ManipalHospitalsIndia Google+: https://plus.google.com/111550660990613118698 Twitter: https://twitter.com/ManipalHealth Pinterest: https://in.pinterest.com/manipalhospital Linkedin: https://www.linkedin.com/company/manipal-hospital Instagram: https://www.instagram.com/manipalhospitals/ Foursquare: https://foursquare.com/manipalhealth Alexa: http://www.alexa.com/siteinfo/manipalhospitals.com Blog: https://www.manipalhospitals.com/blog/
Просмотров: 1106 Manipal Hospitals
5 Sure Signs and Symptoms of Lung Cancer You Should Not Ignore
 
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5 Sure Signs and Symptoms of Lung Cancer You Should Not Ignore Link: https://www.youtube.com/watch?v=SUxKlAVpt5s Please subscribe our channel: https://www.youtube.com/c/livehealthylifeofficial Like us on Facebook: https://www.facebook.com/Live-Healthy-Life-1645151002425115 Follow us on Twitter : https://twitter.com/livehealthylif1 Follow us on Google+ : https://plus.google.com/+LiveHealthyLifeofficial 5 Sure Signs and Symptoms of Lung Cancer Lung cancer is a type of cancer that starts in the lungs. Your lungs are two spongy organs in your chest that absorb oxygen when they inhale and release carbon dioxide when you exhale. Lung cancer is the leading cause of cancer deaths in the United States, both among men and women. Lung cancer takes more lives each year than cancers of the colon, prostate, ovary, and breast combined. People who smoke have the highest risk of lung cancer, although lung cancer can also occur in people who have never smoked. The risk of lung cancer increases with time and the number of cigarettes you have smoked. If you stop smoking, even after smoking for many years, you can significantly reduce your chances of developing lung cancer. Change in breathing If you have trouble breathing or are short of breath very easily, it could be a sign of a lung disease, including lung cancer. If a tumor in the lung blocks the passage of air, you may feel this shortness of breath. It could also happen because the carcinoma fluid can accumulate inside the lungs. Coughing blood Lung cancer can cause bleeding in the airways, which can cause you to hear blood (hemoptysis). Sometimes the bleeding can become severe. The treatments are available to control bleeding. Sudden weight loss If there is a drastic decrease in your weight without a diet or training regimen to base it, it could be a signal that your body is sending to show that a tumor is growing inside you. In general, cancer cells absorb all the energy in the body, resulting in weight loss. However, this is not only a sign of lung cancer but also of any other type of cancer. Chest pain Lung cancer can cause pain in the chest, shoulders or back. Whether the pain is acute and constant or boring and incessant, be sure to notify your doctor immediately. Chest pain can be indicative of many health problems, including lung cancer. Signs for smokers If you are a smoker and have noticed some change in the way you a cough, you should see a doctor immediately. If you are coughing more often, more roughly or coughing up blood, it could be a sign of lung cancer. If you feel a constant whistle in your chest when you breathe, do not ignore it. It could be a tumor blocking the passage of air.
Просмотров: 6016 Live Healthy Life
Signs of Lung Cancer   You Might Have These Symptoms
 
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Twiter : https://twitter.com/HealthB60542247 Google + https://goo.gl/ZXvG4p Most lung cancers do not cause any symptoms until they have spread, but some people with early lung cancer do have symptoms. If you go to your doctor when you first notice symptoms, your cancer might be diagnosed at an earlier stage, when treatment is more likely to be effective. The most common symptoms of lung cancer are: A cough that does not go away or gets worse Coughing up blood or rust-colored sputum (spit or phlegm) Chest pain that is often worse with deep breathing, coughing, or laughing Hoarseness Weight loss and loss of appetite Shortness of breath Feeling tired or weak Infections such as bronchitis and pneumonia that don’t go away or keep coming back New onset of wheezing If lung cancer spreads to distant organs, it may cause: Bone pain (like pain in the back or hips) Nervous system changes (such as headache, weakness or numbness of an arm or leg, dizziness, balance problems, or seizures), from cancer spread to the brain or spinal cord Yellowing of the skin and eyes (jaundice), from cancer spread to the liver Lumps near the surface of the body, due to cancer spreading to the skin or to lymph nodes (collections of immune system cells), such as those in the neck or above the collarbone
Просмотров: 478722 CELEBRITY CBN
Cancers of the lung
 
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This is a short video describing the four most common carcinomas of the lung. I created this presentation with Google Slides. Image were created or taken from Wikimedia Commons I created this video with the YouTube Video Editor. ADDITIONAL TAGS: Cancers of the lung The most common carcinomas that originate in the lung parenchyma Squamous cell carcinoma Adenocarcinoma Large-cell undifferentiated carcinoma Small-cell carcinoma Non-small-cell carcinomas Squamous cell carcinoma Smokers (98%) Often arises centrally/proximally in larger bronchi more than peripheral lung Occurs in bronchi more than larynx and trachea bc flow more turbulent Associated with hypercalcemia (secretes PTH-like cmpd); causing weakness, dehydration, AMS Might see desmosomes and/or keratin accumulation (keratin pearls) Can cause obstruction of airway, atelectasis, collapse of lung Can invade lymphatics Can cause clubbing Squamous cell carcinoma Adenocarcinoma Large-cell undifferentiated carcinoma Small-cell carcinoma Adenocarcinoma Most common carcinoma in nonsmokers (but 80% are smokers) More likely to be peripheral than central/proximal Might see glands and/or mucin production on histology Hypertrophic osteoarthritis (HPO) triad has clubbing, long bone swelling, and arthritis Adenocarcinoma in situ (formerly: "Bronchioloalveolar carcinoma" (BAC)) Lepidic growth pattern, replaces type I pneumocytes, but no invasion of interstitium Can be solitary nodule, multiple nodules (multifocal, bilateral) Presents as cough and dyspnea, again +/- mucinous Squamous cell carcinoma Adenocarcinoma Large-cell undifferentiated carcinoma Small-cell carcinoma Large-cell undif. carcinoma Large cells with prominent nuclei No desmosomes, no keratin, no mucin staining Expression analysis on cDNA microarray Squamous cell carcinoma Adenocarcinoma Large-cell undifferentiated carcinoma Small-cell carcinoma Small-cell carcinoma Exclusively smokers Paraneoplastic syndromes: Secretes hormones: ACTH (can cause Cushing’s), ADH (Na abnormality) Eaton-Lambert (neurologic disorder) Fast-growing, rapid progression, early metastases, often high stage at presentation Highly responsive to chemo/rad treatment Limited → Extensive staging as metastasis outside of hemithorax High N/C ratios, frequent mitotic figures, high percentage of cells in division, salt and pepper chromatin, cells aren’t that small Squamous cell carcinoma Adenocarcinoma Large-cell undifferentiated carcinoma Small-cell carcinoma
Просмотров: 11524 MedLecturesMadeEasy
NSCLC: Immunotherapy Beyond Progression
 
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Panelists Suresh S. Ramalingam, MD; Benjamin Besse, MD, PhD; Giorgio Scagliotti, MD, PhD; and Marina Garassino, MD, discuss the approach of immunotherapy beyond progression for metastatic lung adenocarcinoma after use of a checkpoint inhibitor.
Просмотров: 454 OncLiveTV
Tuberculosis (TB): Progression of the Disease, Latent and Active Infections.
 
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This video and other animations (in HD) for patient education are available for instant download licensing here: https://www.alilamedicalmedia.com/-/galleries/all-animations/respiratory-system-videos Voice by: Qudsi Baker. ©Alila Medical Media. All rights reserved. Support us on Patreon and get FREE downloads and other great rewards: patreon.com/AlilaMedicalMedia All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Tuberculosis, or TB, is one of the oldest and most common infectious diseases. About one third of the world population is believed to be infected with TB. Fortunately, only about 5% of these infections progress to active disease. The other 95% of infected people are said to have a dormant or latent infection; they do not develop any symptoms, and do not transmit the disease. Tuberculosis is caused by a rod-shaped bacterium, or a bacillus, called Mycobacterium tuberculosis. An infection is initiated following inhalation of mycobacteria present in aerosol droplets discharged into the atmosphere by a person with an active infection. The transmission process is very efficient as these droplets can persist in the atmosphere for several hours and the infectious dose is very low – less than 10 bacilli are needed to start the infection. Once in the lung, the bacteria meet with the body’s first-line defense - the alveolar macrophages. The bacteria are ingested by the macrophages but manage to survive inside. Internalization of the bacilli triggers an inflammatory response that brings other defensive cells to the area. Together, these cells form a mass of tissue, called a granuloma, characteristic of the disease. In its early stage, the granuloma has a core of infected macrophages enclosed by other cells of the immune system. As cellular immunity develops, macrophages loaded with bacteria are killed, resulting in the formation of the caseous center of the granuloma. The bacteria become dormant but may remain alive for decades. This enclosed infection is referred to as latent tuberculosis and may persist throughout a person's life without causing any symptoms. The strength of the body’s immune response determines whether an infection is arrested here or progresses to the next stage. In healthy people, the infection may be stopped permanently at this point. The granulomas subsequently heal, leaving small calcified lesions. On the other hand, if the immune system is compromised by immunosuppressive drugs, HIV infections, malnutrition, aging, or other factors, the bacteria can be re-activated, replicate, escape from the granuloma and spread to other parts of the lungs causing active pulmonary tuberculosis. This reactivation may occur months or even years after the initial infection. In some cases, the bacteria may also spread to other organs of the body via the lymphatic system or the bloodstream. This widespread form of TB disease, called disseminated TB or miliary TB, occurs most commonly in the very young, the very old and those with HIV infections. Tuberculosis is generally treatable with antibiotics. Several antibiotics are usually prescribed for many months due to the slow growth rate of the bacteria. It’s very important that the patients complete the course of the treatment to prevent development of drug-resistant bacteria and re-occurrence of the disease.
Просмотров: 423547 Alila Medical Media
Operation of lung cancer
 
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The deadliest form of cancer in the U.S., involving cells that originate in the bronchi or lung. The term includes four cell types: squamous cell (epidermoid) carcinoma, adenocarcinoma, large cell (anaplastic) cancer, and small cell (oat cell) cancer. INCIDENCE In 2013, the National Cancer Institute (NCI) estimated that more than 228,000 people would be diagnosed with lung cancer and that about 159,500 would die of the disease. It is the second most common cancer in both men and women. CAUSES The vast majority are caused by carcinogens in tobacco smoke, including secondhand smoke. Other risks include exposure to carcinogenic industrial and air pollutants (asbestos, uranium, arsenic, nickel, chromium, iron oxides, coal dust, and radioactive dusts), concentrations of radon gas, and familial susceptibility. SYMPTOMS AND SIGNS Symptoms may include persistent cough, chest pain, dyspnea, weight loss, or hemoptysis. Changes in normal respiratory patterns or hoarseness, as well as pneumonia, bronchitis, epigastric pain, symptoms of brain metastasis, arm or shoulder pain, or swelling of the upper body are other possible signs. DIAGNOSIS Diagnostic tests include a chest x-ray, computed tomography (CT) scan, cytological sputum analysis, and bronchoscopy. Other tests include needle biopsy, magnetic resonance imaging (MRI), thoracentesis, thoracotomy, mediastinoscopy, or pulmonary function tests. TREATMENT Treatment includes lung surgery, radiation therapy, and chemotherapy (including epidermal growth factor receptor blockers) often provided serially or in combination. PROGNOSIS People with localized lung cancer have an approx. 5-year survival of 50%. People with widely metastatic lung cancer have a 5-year survival of less than 5%. PATIENT CARE Staging determines the extent of the disease and aids in planning treatment and predicting the prognosis. Lung cancer is relatively difficult to cure but much easier to prevent. Children and adolescents should be discouraged from smoking tobacco products, and current smokers should be assisted in their efforts to quit, e.g., through referrals to local branches of the American Cancer Society (ACS), smoking-cessation programs, individual counseling, or group therapy. SCREENING AND PUBLIC HEALTH Chest x-rays do not show small, early cancers, but computed tomography (CT) scanning can be used to screen people who have a long history of smoking and evidence of emphysema. In this high-risk group, screening detects the disease in its early stages when it is most likely to be curable. Smokers over the age of 55 who undergo annual lung cancer screening with low-dose CT scans have improved survival relative to those who do not. However, the public health costs of mass screening are high compared with the cost of encouraging smokers to quit or teaching teenagers not to start smoking. Pls Subscriptions and Share : Follow us on: https://www.youtube.com/channel/UCFFnAEmlw80lqFPtJ4-DRPg sbs15625@gmail.com https://twitter.com/BariSadik https://www.facebook.com/sadikatulbari.sadik https://www.facebook.com/mats.dmf?ref=hl tabersdictionary.blogspot.com
Просмотров: 19094 Sadikatul Bari Sadik
Staging of Lung Cancer
 
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Learn more about lung cancer at http://www.YouAndLungCancer.com This animation explains how lung cancer staging is a system that doctors use to describe or classify the overall size and spread of the main tumor. Doctors need lung cancer staging information to help plan a patient’s treatment. Lung cancer is classified into several stages - the higher the stage the more advanced the spread of the disease and the more aggressive the treatment strategy. In Stage 0 the cancer is only in the top layers of the cells lining the lung’s air passages and this is the easiest stage to treat. In Stage IV the cancer has spread to the other lung, lymph nodes outside the lungs, and other parts of the body.
Просмотров: 18082 You and Lung Cancer
Osimertinib in Advanced Non–Small-Cell Lung Cancer
 
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EGFR tyrosine kinase inhibitors are standard treatment for non small-cell lung cancer. Despite high tumor response rates, disease progresses in most patients after 9 to 13 months. Is there a way to lengthen progression-free survival? New research findings are summarized in this short video. Full study: http://nej.md/2gymJkj
Просмотров: 5559 NEJMvideo
Lung Cancer - Overview, risk factors & screening - (Part 1 of 3)
 
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This video was developed by the Task Force to provide primary care physicians with key information about lung cancer screening. The video references the Task Force’s 2016 lung cancer guideline recommendations. The video explains disease progression; lung cancer screening; and the Task Force lung cancer screening guideline recommendations, including the overall benefits and harms of screening. Lung cancer: Overview, risk factors & screening The Canadian Task Force on Preventive Health Care is a group of experts who develop recommendations to either screen, or not screen, for specific diseases in primary care. Lung cancer is a disease that occurs when cells in the lung start to grow in an uncontrolled way. The cancer may begin in one or both lungs and could spread to other parts of the body. Lung cancer is one of the most common types of cancer diagnosed in Canada and is the leading cause of cancer-related death among Canadians. The chances of survival 5 years after diagnosis with advanced lung cancer are one of the lowest cancer survival rates in Canada. Lung cancer may not cause any symptoms during the early stages of the disease. By the time people start experiencing symptoms, the cancer is usually at an advanced stage and difficult to treat. Who is at risk for getting lung cancer? Smoking and age are the biggest risk factors for lung cancer. Almost all people who get lung cancer in Canada are over 50, and the disease becomes more common as people age. More than half of new cases of lung cancer are in people older than 70 years of age. Cigarette smoking is the main preventable cause of lung cancer, accounting for more than 80% of cases; other causes include, exposure to radon, second-hand smoke and other air pollutants, occupational exposures to smoke and asbestos, family history and prior radiation to the chest. What does screening mean? When doctor’s screen for lung cancer, it means that they are looking for lung cancer in people who don’t show any signs or symptoms of having the disease. The idea behind screening is that if doctors can detect lung cancer when the disease is at an early stage, they may be able to treat the cancer earlier and thereby lengthen the person’s life. Screening involves casting a wide net, with an imperfect test, to identify people who may have cancer. People with abnormal results will have to undergo extra, more invasive tests to determine if they actually have cancer. The test may also identify those with abnormal results who do not have cancer. The Task Force recommends screening for lung cancer only in people aged 55-74 years who have a history of heavy smoking and who are either current smokers or who quit within the last 15 years. Screening does not apply to people with a history of lung cancer or who are suspected of having lung cancer. That is because screening is done to detect people who have no indication that they may have cancer. People with a history of lung cancer or who have symptoms should be monitored closely by their doctor. If you have any questions, please consult your doctor. For more detailed information on the Canadian Task Force on Preventive Health Care lung cancer screening guideline, and additional resources, please visit www.canadiantaskforce.ca
Lung cancer stages
 
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Lung cancer stages http://www.cancercenter.com/lung-cancer/stages/tab/non-small-cell-lung-cancer-stage-4/ Making an educated treatment decision begins with the stage, or progression, of the disease. Using the results from your diagnostic tests, your care team at Cancer Treatment Centers of America® (CTCA) will develop an appropriate treatment plan for you. If you have been recently diagnosed, we will review your pathology to confirm you have received the correct diagnosis and staging information, and develop a personalized treatment plan for you. If you have had a cancer recurrence, we will perform comprehensive testing and identify a treatment approach tailored to your needs. Small cell lung cancer staging Small cell lung cancer makes up less than 20 percent of lung cancers and is typically caused by tobacco smoking. It often starts in the bronchi, then quickly grows and spreads to other parts of the body, including the lymph nodes. Small cell lung cancer stages are classified in two ways: Limited stage: The cancer is found in one lung, sometimes including nearby lymph nodes. Extensive stage: Cancer has spread to the other lung, the fluid around the lung (the pleura) or to other organs in the body. Non-small cell lung cancer staging Non-small cell lung cancer staging uses the TNM system: Tumor (T) describes the size of the original tumor. Lymph node (N) indicates whether the cancer is present in the lymph nodes. Metastasis (M) refers to whether cancer has spread to other parts of the body, usually the liver, bones or brain. A number (0-4) or the letter X is assigned to each factor. A higher number indicates increasing severity. The letter X means the information could not be assessed. For instance, a T1 score indicates a smaller tumor than a T2 score. Once the T, N and M scores have been assigned, an overall stage is assigned. Stages of non-small cell lung cancer: Occult stage non-small cell lung cancer: Cancer cells are found in sputum, but no tumor can be found in the lung by imaging tests or bronchoscopy, or the tumor is too small to be checked. Stage 0 non-small cell lung cancer: Cancer at this stage is also known as carcinoma in situ. The cancer is tiny in size and has not spread into deeper lung tissues or outside the lungs. Stage I non-small cell lung cancer: Cancer may be present in the underlying lung tissues, but the lymph nodes remain unaffected. Stage II non-small cell lung cancer: The cancer may have spread to nearby lymph nodes or into the chest wall. Stage III non-small cell lung cancer: The cancer is continuing to spread from the lungs to the lymph nodes or to nearby structures and organs, such as the heart, trachea and esophagus. Stage IV non-small cell lung cancer: The cancer has metastasized throughout the body and may now affect the liver, bones or brain. Please SUBSCRIBE to My Channel for Daily Videos Lung cancer stages https://youtu.be/xlgni5trFfc
Просмотров: 768 Health Tips For Men & Women
Diagnosis of Metastatic Lung Adenocarcinoma
 
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Heather Wakelee, MD, discusses the diagnosis of a 70-year old patient with metastatic lung adenocarcinoma and the variable prognoses for this disease type. For more resources and information regarding anticancer targeted therapies: http://targetedonc.com/
Просмотров: 577 Targeted Oncology
What to Do After Progression on Immunotherapy and for Non-Driver NSCLC
 
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In this segment, Alexander Drilon, MD; Tracey Evans, MD; Vali Papadimitrakopoulou, MD; Mark Socinski, MD; and Jared Weiss, MD, discuss sequencing after disease progression following immunotherapy and suggest when bevacizumab may be appropriate.
Просмотров: 648 OncLiveTV
Continuation of ceritinib beyond disease progression in ALK-positive NSCLC
 
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At the 6th European Lung Cancer Conference (ELCC), held in Geneva, Switzerland, from 13–16 April 2016, Enriqueta Felip, MD, PhD, from Vall d’Hebron Institute of Oncology, Barcelona, Spain, discusses results from a retrospective study showing the continuation of ceritinib beyond disease progression is associated with prolonged post-progression survival in patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC).
Просмотров: 39 VJOncology
Cancer, How Cancer Starts, How Cancer Spreads, Where and Why, Animation.
 
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This video and other related images/videos (in HD) are available for instant download licensing here : https://www.alilamedicalmedia.com/-/galleries/images-videos-by-medical-specialties/medical-genetics ©Alila Medical Media. All rights reserved. Support us on Patreon and get FREE downloads and other great rewards: patreon.com/AlilaMedicalMedia All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Perfect for patient education. The number of cells in a tissue is determined by the balance between cell division and cell death. Uncontrollable cell division leads to formation of abnormal growths called tumors. Tumors can be benign or malignant. Benign tumors are slow-growing and constrained by surrounding connective tissue so they do not spread to other organs. They can still be harmful or even kill by pressing on nearby nerves, brain tissue or blood vessels. Examples of benign tumor include pituitary tumors which may press on optic nerves and cause loss of vision. Cancers are malignant tumors - tumors that can spread beyond of the limit of original organ where it comes from and to other organs of the body. How cancer starts Cancer starts from damage in the DNA of a cell. This DNA damage is called mutation. Mutations happen when the cell duplicates its DNA prior to cell division and makes mistakes. These damages are usually detected and repaired before the cell can divide but sometimes, some of them may be ignored and transferred to daughter cells. If the mutation is located in one of many genes that control the cell cycle, it may affect the regulation of cell cycle in the cell carrying it, and make the cell divide faster than it supposed to. Usually, one mutation is not enough to cause cancer, but as it makes the cell cycle control less reliable, many more DNA damages/mutations would go unnoticed. Cancer is usually the result of accumulation of many mutations of genes involved in cell cycle control and DNA repair. This commonly happens over a long period of time, over many rounds of cell divisions, and this explains why cancers are more common in older people. Some people are said to be predisposed to cancer. This is because they are born with a mutation that makes them more likely to develop a certain type of cancer. This mutation alone is not enough to cause cancer but it starts the process of making cells cancerous. The person carrying it is one step further down the road towards developing a cancer than others who do not have the mutation. How cancer spreads Cancer cells do not stick together like normal cells, they move and invade nearby tissues, organs, this is local spread. They may also spread to further away organs by means of blood and lymph circulation, this is systemic spread. Metastasis is the spreading of cancers to non-adjacent organs. Cancer cells from the original tumor, or primary cancer, can break out and maybe taken up by a blood or a lymph vessel for a ride throughout the body. They can then squeeze out from the vessels into other tissues and start a new tumor growth in the new location which will become secondary cancer. Where do cancers usually spread and why? While travelling in the bloodstream, cancer cell usually stops at the first place where the vessel getting so narrow that it gets stuck. As blood flow from most organs goes to the capillaries of the lungs, this is where cancers spread the most. Lungs are indeed the most common site of secondary cancers. Likewise, while travelling in the lymphatic system, cancer cells commonly get stuck in nearest lymph nodes, where the vessels get narrower. This is the reason why surgeons usually remove nearby lymph nodes when removing tumors.
Просмотров: 156037 Alila Medical Media
EGFR-Positive NSCLC: Treatment at Progression
 
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Panelists Suresh S. Ramalingam, MD; Marina Garassino, MD; Giorgio Scagliotti, MD, PhD; and Benjamin Besse, MD, PhD, provide perspective on the best therapeutic approach for EGFR-positive non–small cell lung cancer after progression on upfront osimertinib.
Просмотров: 576 OncLiveTV
Treatment Recommendations for Stage 3 Non-Small Cell Lung Cancer
 
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Julie R. Brahmer, MD, associate professor of oncology and co-director of the Upper Aerodigestive Department at the Bloomberg Kimmel Institute for Cancer Immunotherapy, John Hopkins, Medicine, discusses the change in standard of care for patients with stage 3 non-small cell lung cancer (NSCLC). Durvalumab (Imfinzi) has been approved by the FDA as a consolidation therapy. This approval came based on data from the PACIFIC trial, which found a significant advantage in control of disease as well as progression-free survival, Brahmer says. She added that this trial compared the addition of durvalumab to a placebo after concurrent chemotherapy and radiation. Investigators did not find an increase in overall toxicity with the addition of durvalumab. Brahmer hopes they will have the overall survival data soon from this trial, but as of now, the addition of durvalumab after concurrent chemotherapy and radiation is the new standard of care for patients with unresectable stage 3 disease. Durvalumab has shown to improve survival of these patients. For more resources and information regarding anticancer targeted therapies in lung cancer: http://www.targetedonc.com/resource-center/lung
Просмотров: 49 Targeted Oncology
The changing face of lung cancer treatment
 
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Dr Sanjay Popat talks about how treatment for lung cancer patients has transformed their lives in recent years thanks to a host of promising new treatments and drugs
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Newly Revised TNM Lung Cancer Staging System
 
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Просмотров: 2832 123radiology
How Vivid Images are Reducing Lung Cancer Deaths
 
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(Visit: http://www.uctv.tv) Dr. Brett Elicker discusses tools for lung cancer screenings that are helping reduce deaths from the disease. Elicker is an Associate Professor of Clinical Radiology and Chief of the Cardiac and Pulmonary Imaging Section at the University of California, San Francisco. Recorded on 10/13/2015. Series: "UCSF Osher Center for Integrative Medicine presents Mini Medical School for the Public" [12/2015] [Health and Medicine] [Show ID: 30131]
Просмотров: 1964 University of California Television (UCTV)
Stage 4 Lung Cancer Metastasized to Brain & Bone
 
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Diagnosed with Stage 4 Lung Cancer Jan 2015 "Today the brain cancer is basically gone. and the bone cancer they arent saying is gone, they just cant find it. Lung cancer has shrunk more than a third"
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Targeted Treatment for Lung Cancer After Progression
 
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http://cancerGRACE.org/ Dr. Geoffrey Oxnard of Dana-Farber Cancer Institute discusses whether or not patients on targeted therapies, such as EGFR inhibitors, should stay on those therapies after their cancers begin to grow again. February 2014. GRACEcast 213 Lung
Antioxidants accelerate lung cancer progression in mice
 
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Interview with Prof Martin Bergö and Prof Per Lindahl, regarding a new study that shows that antioxidants accelerate lung cancer progression in mice. The findings were published in the journal Science Translational Medicine in January, 2014.
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What Is Stage 5 Lung Cancer?
 
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Stage iv non small cell lung cancer the has metastasized throughout body and may now affect liver, bones or brain 30 jun 2017 it's also called hidden. Symptoms & stages of lung cancer. Lung cancer stages what are the stages? What of lung 1 4, limited vs non small cell survival rates, by stage. Cancer cells haven't spread into your deeper lung tissues or outside lungs. Small cell lung cancer stages american society. Year survival by stage for lung cancer. Lung cancer stages what are the stages? . Staging & prognosis cancer council nswfree to breathe lung news medical. Stage iv lung cancer is cure possible? Ncbi nih. Non small cell lung cancer stages american societycancer research uk. Stage 0 your tumor is very small. Ctca cancercenter lung cancer stages url? Q webcache. Html 28 jan 2013 there are two main categories non small cell and carcinoma several types of lung cancer, each having its own characteristics. Stage ii the disease may have spread to your lymph nodes near lungs stage iib lung cancer describes a tumor larger than 5 cm but less 7 wide that has. What is stage 4 lung cancer life expectancy? Verywell. From early warning signs to stage iv bronchioloalveolar carcinoma, the following article features causes, symptoms, types, and 21 nov 2016 stages of lung cancer; What are symptoms cancer? A type cancer caused by asbestos exposure, is 5 10 percent even when such as coughing fatigue do occur, people think they due other causes. 11 aug 2002 my mother has lung cancer for the last several years and now has brain cancer. Or, a stage iib cancer can be tumor more 16 may 2016 survival rates tell you what portion of people with the same type and are still alive certain amount time (usually 5 years) 2 mar 2017 partially clogs airways, but this has not caused entire lung to collapse or develop pneumonia. The progression of lung cancer. These statistics are from one area of keywords chemotherapy, cure, lung cancer, stage iv in patients with brain metastases, surgical resection achieves 5 year survival rates between 11. Googleusercontent search. Stage iii non small cell lung cancer the is continuing to spread from lungs lymph nodes or nearby structures and organs, such as heart, trachea esophagus. Stage i cancer is in your lung tissues but not lymph nodes. She has undergone radiation treatment and is currently still 22 jun 2016 stages of lung cancer can help a doctor identify the best course less than 5 percent cancers diagnosed each year are survival rates by stagecancer non small cell detection diagnosis staging. Non small cell lung cancer treatment (pdq) patient version symptoms, stages, and emedicinehealth. T2a tumour is between 3 cm and 5 cm; T2b learn about what each stage of lung cancer means based on whether you have a tumor up to wide that has not spread any lymph nodes or other 17 jan 2016 there are four main stages in 2007, study called people with 1a will survive for at least years after diagnosis, 13 apr 2017 occult non small cell cancer;
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Major changes in treatments for patients with metastatic squamous cell lung cancer
 
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Johan Vansteenkiste, MD, PhD of University Hospitals Leuven, Belgium discusses major changes in first-line treatment for patients with metastatic squamous cell lung cancer. Firstly, overall survival (OS) and progression-free survival (PFS) was improved when an epidermal growth factor receptor (EGFR) targeting antibody such as necitumumab was added to traditional gemcitabine and platinum-based chemotherapy. This progress is crucial for squamous cell lung cancer patients. Furthermore, first-line immunotherapy with pembrolizumab was shown to be superior to chemotherapy in patients expressing high levels of programmed death-ligand (PD-L1). In addition, immunotherapy has changed treatments for relapsed setting, second-line, or third-line patients. These results are less important for adenocarcinomas where there are more treatment options, than squamous cell carcinoma where there are few alternatives. Recorded at the 2016 World Conference of Lung Cancer (WCLC) of the International Association for the Study of Lung Cancer (IASLC) in Vienna, Austria.
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Lung Cancer Rx Might Outperform Chemo
 
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http://www.dailyrx.com/ A new study found evidence that immunotherapy, which uses the body's own immune system to fight a disease, helped patients with lung cancer live longer than patients treated with chemotherapy. "In the 20 years that I’ve been in practice, I consider this a major milestone,” said lead study author Julie Brahmer, MD, of Johns Hopkins Medicine's Sidney Kimmel Comprehensive Cancer Center in Baltimore, in a news release. Dr. Brahmer and team compared traditional chemotherapy treatment to treatment with an immunotherapy medication, nivolumab (sold under the brand name Opdivo). The study involved 272 patients with squamous-cell non-small-cell lung cancer, a common form of lung cancer where cancer cells form in the tissue lining the lungs. These patients had all received initial chemotherapy, but their cancer was still progressing. In chemotherapy, doctors give patients powerful drugs that attack cancer cells. The study patients were split into two groups. In the first group, 135 patients received the immunotherapy drug nivolumab. The second group of 137 patients received docetaxel (sold under the brand name Taxotere), a chemotherapy drug. Overall, Dr. Brahmer and team found better results among the nivolumab group — who had a 41 percent lower relative risk of dying from lung cancer than the chemotherapy group. The immunotherapy patients had a median overall survival of 9.2 months, compared to six months in the chemotherapy group. The immunotherapy patients also had a median of 3.5 months with out any disease progression, compared to 2.8 months in the chemo group. And after one year, 42 percent of the patients taking nivolumab were still alive, compared to only 24 percent of the chemotherapy group — nearly a doubled survival rate among the immunotherapy patients. The patients taking nivolumab also reported fewer and less severe side effects. Only 7 percent of this group reported severe side effects, compared to 55 percent of the chemo patients.
Просмотров: 485 dailyRx
Diagnosing Lung Adenocarcinoma: Biopsying Adequate Tissue
 
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Gerald J. Berry, MD, provides insight on the techniques for diagnosing lung adenocarcinoma, including how they inform clinical decision making and whether they are necessary at disease progression, and gives his recommendations for acquiring necessary tissue for biopsying.
Просмотров: 767 OncLiveTV
DYING FROM LUNG CANCER -- description of the dying process
 
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DYING FROM LUNG CACNER - description of the dying process.
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1.1 Multi Step Tumorigenesis
 
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The characteristics of cancer cells Cancer cells can often be distinguished from normal cells by microscopic examination. They are usually less well differentiated than normal cells or benign tumor cells. The presence of invading cells in an otherwise normal tissue section is used to diagnose a malignancy A colonic crypt Stem cells are housed in the base of the crypts Stem cells give rise to the transit-amplifying compartment where most cell production occurs. Multi Step Tumorigenesis The formation of a tumor is a complex process that usually proceeds over a period of decades. Normal cells evolve into cells with increasingly neoplastic phenotypes through a process termed tumor progression. Rarely does it proceed far enough at any single site to make us aware of a clinically detectable tumor mass. Multi Step Tumorigenesis Tumor progression is driven by a sequence of randomly occurring mutations and epigenetic alterations of DNA that affect. The genes controlling cell proliferation and survival Other traits associated with the malignant cell phenotype. Most human cancers develop over many decades of time Epidemiologic studies have shown that age is a surprisingly large factor in the incidence of cancer. The risk of dying from colon cancer is as much as 1000 times greater in a 70-year-old man than in a 10-year-old boy. The incidence of lung cancers Cigarette smoking was relatively uncommon until World War II, when large numbers of men acquired the habit encouraged in part by the cigarettes they received in their rations. Thirty years later, in the mid-1970s, the rate of lung cancer began to climb steeply Cigarette smoking spread throughout the world and peaked in 1990, lung cancer mortality which currently exceeds 1.1 million deaths annually will peak only sometime in the decade after 2020. The incidence of lung cancers Tumorigenesis is a Multi-Step process Assume that a sequence of unlikely events is required in order for a tumor to appear many of these events happen at comparable frequencies in all of us. These assumptions indicate that as we grow older, virtually all of us will have completed some but not all of the steps of tumor progression. Cancer incidence increase with age Cancer incidence should increase with age because it can take decades for the required multiple mutations to occur. Age at death from epithelial cancers Epidemiology provides another important insight into the multi-step nature of tumorigenesis. If we examine the frequencies of mesothelioma in humans (caused largely by asbestos exposure and smoking) skin cancer in mice (induced by repeated carcinogen painting) (see next slide) It becomes apparent that the formation of each of these tumors requires an extended period of repeated exposure to carcinogens it is the duration of this exposure (rather than the absolute age of exposed individuals or the age when exposure began) that determines the timing of the onset of detectable disease Carcinogens increase the rate of tumor progression
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How does cancer spread through the body? - Ivan Seah Yu Jun
 
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View full lesson: http://ed.ted.com/lessons/how-does-cancer-spread-through-the-body-ivan-seah-yu-jun Cancer usually begins with one tumor in a specific area of the body. But if the tumor is not removed, cancer has the ability to spread to nearby organs as well as places far away from the origin, like the brain. How does cancer move to these new areas and why are some organs more likely to get infected than others? Ivan Seah Yu Jun explains the three common routes of metastasis. Lesson by Ivan Seah Yu Jun, animation by Andrew Foerster.
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What Is The Survival Rate For Stage 2 Lung Cancer?
 
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Stage 2 non small cell the overall survival rate with stage 2a lung cancer is 30 percent and for 2b cancer, what are symptoms, how it treated, prognosis? . This typically survival rates for non small cell lung cancer, by stage. Patients with stage ii non small cell lung cancer without spread to lymph nodes patients ia nsclc have a relatively high rate of long term survival 7 aug 2017 find out about for people in the uk. Stage ii non small cell lung cancer survival statistics of patients with without treatment prognosis stage according to tumor news medical. For stage ii sclc, the 5 year relative survival rate is about 19. T1a – Tumour is less than 2 cmt (tumour); T1b between cm and 3 cm; T2a once the primary tumor found stage established, treatment choices although cure rate for 1 non small cell lung cancer results demonstrated that radiation alone produced an average survival time of over 34 months [2] approximately 51 Lung rates by type verywell. The overall survival rate, that is the percent of people who are expected to be alive 5 years after a diagnosis stage 2 lung cancer approximately 30. The numbers knowing the stage of lung cancer helps doctor plan best treatment for you. Googleusercontent search. Your doctor can give you more information about your own outlook (prognosis)more than 60 out of 100 people (more. Treatment of non small cell lung cancer in older persons. See data for sex, age, trends over time lung cancer survival by stage at diagnosis 4 feb 2013 to retrieve prognosis studies in pubmed, we employed mortality rate i ii (median 10 months). Lung cancer survival rates by type and stage verywell. Small cell lung cancer survival rates, by stage. Stage 2 non small cell lung cancer verywell. 2005 aug;49(2) 181 6prognosis of stage ii non small cell lung cancer according to tumor and nodal status at diagnosis 17 jan 2016 there are many different types of lung cancer, but the two main types are small the survival statistics for stage 4 lung cancer are very low a stage i lung cancer is a small tumor that has not spread to any lymph nodes, sometimes, stage ii tumors can be removed with surgery, and other times, the type and stage of nsclc and the patient's overall health influence prognosis yes, stage 2 lung cancer is potentially curable in general. For individuals with large tumors that have not yet spread to any lymph nodes, the survival rate may be somewhat higher stage 1 non small cell overall 5 year for 1a lung cancer is 49 percent and 1b 45. Lung cancer stages, survival rates, and more healthline. Stage 0, stage 1, and 2 lung cancer. Lung cancer survival rates by type and stage verywell what is 2 lung life expectancy verywell 2249272 url? Q webcache. The latest lung cancer survival statistics for the uk health professionals. Staging & prognosis cancer council nsw. 22 jun 2016 do lung cancer stages affect survival rates? Stage 2, cancer is located in the lungs and maybe in the lymph nodes near the lungs learn more about the
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ALK Positive Forum Scanning for Progression
 
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http://cancerGRACE.org/ How often should ALK patients receive scans to determine if their disease has progressed in various parts of the body? GRACEcast 191 Lung Video
Surviving With Metastatic Lung Cancer Thanks to Research
 
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November is Lung Cancer Awareness Month. Learn how cancer targeted therapy and clinical trials are helping Ginger live well with stage 4 lung cancer: http://the.aacr.org/kr3E
Просмотров: 18149 American Association for Cancer Research
Lung Cancer Series - ALK Gene-mutated Lung Cancer (English Version-B)
 
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Lung cancer is the top cancer killer in Hong Kong, contributing to more than 3000 deaths every year. The prevalence of Non-Small Cell Lung Cancer (NSCLC), a subtype of lung cancer, has been increasing in recent years. A Japanese clinical study, published in 2007, showed that NSCLC can be caused by mutation and rearrangement of a gene called anaplastic lymphoma kinase, the ALK gene. The study showed that approximately 3-7% of these NSCLC patients would have such gene rearrangement, which can stimulate the survival, proliferation and metastasis of tumour cells. To target this life-threatening cause of cancer, recent years there has been ground-breaking discovery of ALK gene-targeted therapy. Many patients received positive response to this therapy and their disease progression has been controlled. We are honoured to have Dr Patricia Poon, a clinical oncologist in Hong Kong in this series to tell us more about this new cancer treatment regimen and methods of getting ALK gene testing; we also invited two guests, Jennifer and Tammy to share with us their stories of fighting lung cancer. We also set up the ALK Lung Cancer Patient Care Group on Facebook to provide a platform for lung cancer patients to share their experiences and to support each other on their roads of fighting cancer. https://www.facebook.com/groups/224232227778127/ Cancer Information, your companion to fighting cancer http://www.cancerinformation.com.hk/
Просмотров: 950 癌症資訊網
Treatment After Progression on Anti-VEGF Therapy
 
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Benjamin P. Levy, MD, explains how he would manage a patient with advanced-stage squamous non–small cell lung cancer who has a response to the ramucirumab and docetaxel regimen but develops further disease progression. For more resources and information regarding anticancer targeted therapies: http://targetedonc.com/
Просмотров: 18 Targeted Oncology
Lung Cancer Vaccine MAGE-A3 Does Not Improve Disease-Free Survival in Resected Lung Cancer
 
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At ESMO 2014, Prof Johan F. Vansteenkiste summarises the results of the MAGRIT trial, a phase III trial which showed that MAGE-A3 cancer immunotherapy did not increase disease-free survival in patients with resected NSCLC.
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Lung Cancer - Harms & Benefits - (Part 3 of 3)
 
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This video was developed by the Task Force to provide primary care physicians with key information about lung cancer screening. The video references the Task Force’s 2016 lung cancer guideline recommendations. The video explains disease progression; lung cancer screening; and the Task Force lung cancer screening guideline recommendations, including the overall benefits and harms of screening. Lung Cancer: Harms & Benefits What are the possible benefits of lung cancer screening with a low-dose CT scan? Let’s imagine that we screen 1000 people aged 55-74 who have a history of heavy smoking and are either current smokers or quit within the last 15 years. And let’s say that we screen them once a year for three years, as was done in a recent research study. 13 of the 1000 people screened will die of lung cancer, but 16 to 17 out of 1000 would die of lung cancer if they were not screened. So 3 to 4 people out of a 1000 will be saved by being screened for lung cancer. What are the possible harms of lung cancer screening with low-dose CT scan? Screening for lung cancer with low dose CT can also cause harms. Out of 1000 people screened, 351 will receive an abnormal test result and will have to undergo further testing to find out that they don’t have lung cancer; this is known as a “false positive test result.” Of the people who undergo additional testing, 1 to 3 will experience major complications from the tests, such as a collapsed lung or severe pain. 40 people with abnormal testing will be diagnosed with lung cancer, but 7 of these people will be diagnosed with a form of lung cancer that may never have caused any health problems for them. This is called overdiagnosis, and it can lead to unnecessary treatments for lung cancer, like surgery, radiotherapy, or chemotherapy; these treatments may cause harm. So you see that if you choose screening, there is a possible benefit: 3 people saved from dying of lung cancer, but likely also harms: false positive results, complications from extra tests, and treatment that was not needed. These benefits and harms have to be taken into account in your decision. This recommendation means that the Task Force has placed a higher value on the benefit of a small decrease in lung cancer mortality, and a lower value on the possible harms of screening among heavy smokers. We suggest you have a discussion with your doctor to talk about your values and preferences and come to a shared decision on screening. For more detailed information on the Canadian Task Force on Preventive Health Care lung cancer screening guideline and additional resources, please visit www.canadiantaskforce.ca
What Is Lung Cancer?
 
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The statistics on lung cancer can be quite alarming which is why it's important to know the signs. What is lung cancer? What are it's causes and key symptoms? Watch this video to find out, or find out more about the disease on our website: http://www.cancerresearchuk.org/about-cancer/lung-cancer
Просмотров: 948 Cancer Research UK
Gefitinib with Chemotherapy does not Significantly Improve Progression-Free Survival Lung Cancer
 
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At ESMO 2014, Prof Tony Mok presents the results of the IMPRESS trial. This phase III trial showed that continuation of gefitinib with chemotherapy versus chemotherapy alone provided no significant improvement in progression-free survival in patients with EGFR mutation-positive lung cancer who previously failed to respond to first-line gefitinib.
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EGFR liquid biopsies: a step forward in lung cancer monitoring
 
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A liquid biopsy is a simple, non-invasive alternative to surgical biopsies that enables doctors to use a simple blood sample to discover a range of information about a tumour. Traces of the cancer’s DNA in the blood can give clues about which treatments are most likely to work for a specific patient. The test can detect epidermal growth factor receptor (EGFR) gene mutations, which occur in 10-35% of patients with non-small cell lung cancer (NSCLC). To learn more about the role of liquid biopsies in monitoring lung cancer, detecting disease progression and identifying patients likely to respond to tyrosine kinase therapy, visit http://www.roche.com/liquid-biopsy. Subscribe to our YouTube channel now: https://www.youtube.com/user/roche?sub_confirmation=1 Get in touch with us: https://www.roche.com/ https://www.facebook.com/RocheCareers https://www.linkedin.com/company/roche https://twitter.com/roche Roche has been committed to improving lives since the company was founded in 1896 in Basel, Switzerland. Today, Roche creates innovative medicines and diagnostic tests that help millions of patients globally. Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and neuroscience. For more information and insights visit: https://www.roche.com/
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CNS Disease in ALK-Positive NSCLC: Monitoring and Systemic vs. Radiation Therapy
 
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Dr. Ross Camidge, University of Colorado, discusses management of CNS progression for ALK-positive NSCLC including monitoring frequency and preferences between systemic and radiation therapy. http://cancergrace.org/lung/2016/04/13/gcvl_lu_cns_disease_alk-positive_nsclc_monitoring_systemic_radiation_therapy/