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Bisphosphonates and Cancer
 
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http://www.melioguide.com/free-course Mary-Ann Dalzell, an oncology clinical specialist, discusses the role of bisphosphonates in treating cancer.
Просмотров: 400 Margaret Martin
Do Bisphosphonates Reduce Cancer Risks?
 
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What Matters: Dr. William J. Gradishar, associate editor of The Oncology Report, discusses the conflicting results from multiple clinical trials over the last decade and whether bisphosphonates reduce cancer recurrence and metastatic risk. For complete coverage of the 2011 San Antonio Breast Cancer Symposium, visit http://tinyurl.com/7xn5oxt
Просмотров: 217 MDedge
Osteoporosis Drug Brings New Hope To Breast Cancer Treatment
 
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According to findings from the University of Sheffield, using bisphosphonates — drugs for osteoporosis — could also help stop the spread of cancer. Follow : http://www.twitter.com/ See more at http://www.newsy.com Transcript: Findings from researchers at England's University of Sheffield were published Wednesday that could be a serious game changer when it comes to treatment for the spread of breast cancer. Like most cancers, breast cancer has the ability to spread throughout the body, making treatment all the more difficult and slimming chances of survival. One of the places it can spread is to the bones. And that is where this study comes into play — hopefully helping to stop cancer from spreading, especially to bones. According to findings published in the journal Nature, the spread "of breast cancer to the bone affects approximately 85% of patients with advanced disease and renders them largely untreatable." The big takeaway here has to do with an enzyme called lysyl oxidase, or LOX. That enzyme is secreted from cancerous cells in the breasts and can cause the breakdown of bone, making the body more susceptible for cancer to spread. The researchers say the findings add "weight to the growing body of evidence supporting the role of bisphosphonates in stopping secondary breast cancer in its tracks." (Video via The University of Sheffield) Bisphosphonates are a class of drug typically used to treat osteoporosis, or to slow the harsh impact chemotherapy can have on bones. (Video via Rexall) A doctor not affiliated with the University of Sheffield said this: "Certainly a lot of the treatments we use for breast cancer do cause bone loss and the bisphosphonates are used to prevent that or to improve bone density," Dr. Sharon Giordano explained. Using bisphosphonates to not only strengthen bone but also prevent the spread of cancer is a method researchers in the University of Sheffield study found worked in animal tests. According to Katherine Woods, from Breast Cancer Campaign and Breakthrough Breast Cancer, "The reality of living with secondary breast cancer in the bone is a stark one, which leaves many women with bone pain and fractures that need extensive surgery just when they need to be making the most of the time they have left with friends and family." According to Woods, the spread of breast cancer to other areas of the body kills about 1,000 a month in the U.K. **A previous version of this video did not specify that approximately 85 percent of advanced breast cancer patients — not breast cancer patients with all stages of cancer — experience metastasis to the bone."** Sources: Getty Images http://www.gettyimages.com/detail/news-photo/scientist-uses-a-pipette-to-add-a-precise-volume-of-liquid-news-photo/463580696 Healthline http://www.healthline.com/advanced-breast-cancer/anatomy-animations#2/how-and-where-cancer-spreads Wikimedia Commons https://commons.wikimedia.org/wiki/File:Blausen_0686_Osteoporosis_01.png Nature http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14492.html The University of Sheffield http://www.eurekalert.org/pub_releases/2015-05/uos-sik052615.php YouTube https://www.youtube.com/watch?v=99eP4T-8LSE YouTube http://www.youtube.com/watch?v=3CFirK3wfFQ The University of Texas MD Anderson Cancer Center https://www.youtube.com/watch?v=sXqqhGLMiTk National Institutes of Health https://commons.wikimedia.org/wiki/File:003783568lg_Alendronic_acid_35_MG_(as_alendronate_sodium_45.7_MG)_Oral_Tablet.jpg BBC http://www.bbc.com/news/health-32901133 Image via: National Cancer Institute https://visualsonline.cancer.gov/
Просмотров: 1581 Newsy Science
Say No to Bisphosphonates
 
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Say No to Bisphosphonates Bisphosphonates cause a systemic subclinical toxicity which may erupt as osteonecrosis. Bisphosphonates are structural analogues to calcium pyrophosphate in bone and bind to calcium in the skeleton. The bisphosphonates story illustrates the ills of medicine: Useless and improper treatment, and false interpretation of clinical trials. Bisphosphonates are a class of drugs that prevent the loss of bone density, used to treat osteoporosis and similar diseases Bisphosphonates have become an important treatment for the palliation of metastatic bone disease. Their increasing use has lead to the recognition of toxicities that can lead to substantial morbidity for the patient with advanced cancer. This case presentation highlights toxicities associated with bisphosphonate use and provides some guidelines on the use of bisphosphonates and management of these toxicities. The most important predisposing factors for development of bisphosphonate-associated ONJ are the type and total dose of bisphosphonate (potency) and a history of trauma, dental surgery, or dental infection in the jaw. There is a strong association with jaw trauma such as dental extractions
Просмотров: 168 Gershom Zajicek M.D,
Professor Ingunn Holen and research into bisphosphonates for breast cancer
 
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Bisphosphonates are drugs that strengthen bones, and are used to treat osteoporosis, but also to help protect bones when breast cancer spreads to the skeleton – known as secondary breast cancer. Professor Ingunn Holen talks about her research into secondary breast cancer, and how bisphosphonates could be used to treat the disease in the future. Read more about Professor Holen’s research:
Просмотров: 311 Breast Cancer Now
What happens if you have cancer in your bones ? |Best Health Answers
 
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Overview of metastatic cancer in bones webmd. Bone cancer survival rate, causes, types, and treatment. Uconn musculoskeletal institute. Cancer that leads to bone metastasis have started in your breast, prostate, lungs, or other parts of body. If you think might have a bone tumor, see your doctor as soon Bone metastasis when cancer spreads to the bones. Ewing's sarcoma most commonly occurs between age 5 and 20. Bone cancer types, causes & symptoms healthline. University of mcancer bone metastasis url? Q webcache. Bone cancer teenagers and young adults bone metastases canadian society. Benign and malignant bone tumors. Each year, about 100,000 americans with cancer find out that the has spread to their bones. Osteosarcoma occurs most commonly in older children, teenagers, and if they have spread outside of the bone, survival rate drops to 15. Other signs of bone cancer include swelling, a lump, and or the breaking. Bone pain managing side effects chemocare. Cancer cells in people who develop secondary cancer the bone usually know they have a primary. What is secondary bone cancer? Understanding macmillan cancer symptoms center everydayhealth. Bone metastasis when cancer spreads to the bones. Secondary bone cancer the christie nhs foundation trust. If the cancer is localized (has not spread), prognosis usually good. Back to worrying about cancer can have a big impact on your feelings 10, advances in medical research made it possible for doctors catch example, pain arm after lifting heavy objects or leg if you experience any of these bone symptoms, contact rare type and want know more, could talk macmillan. Blood and bone marrow cancers johns hopkins kimmel cancer diagnosis nhs choices. It be hard for you to do any kind of your normal activities. They can talk to you about your symptoms, and arrange tests if they feel osteoblastic metastases often happen when prostate cancer spreads the bone. Googleusercontent search. If you have bone cancer american society. The information standard health and care you can trust. Bone metastasis or bone mets occurs when cancer cells from the primary for example, if prostate has metastasized into bone, it is treated be aware of your own body and share any concerns that you have with doctor fracture might happen a fall injury, but weak can also break you've been diagnosed had in past, these cancers not found until they cause pain makes person go to. Cancer in bones webmd. Bone metastasis be the first sign that you have cancer, what happens in bones? If secondary breast cancer vertebrae (the bones your spine) and a fractures or collapses it can 27, when prostate spreads to Written by susan talk doctor if any of above symptoms 26, bone occurs tumor forms. If you have bone metastases, your healthcare team will create a treatment but i'll answer questions at the end about what happens if delay. Multiple myeloma (bone marrow cancer) signs, symptoms ask the expert online conference metastatic breast cancer. If you or a family member has just been diagnosed with cancer of the blood bone marrow, your mind probably is swimming questions. It is not contagious you cannot catch it from someone else. The aim of treatment is usually to control the cancer and your symptoms so, if started in lung has spread bones, areas this important because primary tells doctor which type you need. That surgical intervention occurs without having to amputate the limb 1, some cancers, such as multiple myeloma, start in bones while other breast, prostate, lung, and kidney have a primary bone cancer where originates. Cancer spread to the bone. The doctor will ask you questions about your health and do a physical exam. Bone cancer greatly depends on the location and stage of when you're first diagnosed 22, your mnt there are many types bone cancer, pictured here is myeloma marrow. For example, your risk of developing a primary bone tumour is increased if you have doctor suspects that cancer, are likely to this happens, it's called secondary cancer or metastasis. Cancer bone cancer symptoms, signs, treatment, survival rate, types metastasis mayo clinic. The most common cancers that spread to do so are read about bone cancer prognosis, treatment, symptoms, signs, survival rate, types, metastatic, and stages. Multiple myeloma, the most common primary bone cancer, is a malignant tumor of marrow. If bone metastasis affects your marrow, you have other symptoms related a tumor that occurs near or in joint cause the to swell and if with breaks, fractures, leg, it can lead pronounced limp. University of finding bone metastases american cancer society. Bone metastases when cancer spreads to the bones health bone symptoms and signs spread. It affects the hard tissue that provides outer layer of your bones. Stages and progression of breast cancer moose doc. If you already have a source or cause for your pain, it is important to follow healthcare if this happens, it's called secondary cancer metastasis. Advanced bladder canc
Просмотров: 220 BEST HEALTH Answers
Side Effects of Bisphosphonates
 
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One of the most popular drugs to treat osteoporosis today is the Bisphosphonates category. These drugs are widely used because they are very effective at prevening bone loss and fractures, but they have side effects such as stomach irritation.
Просмотров: 2069 Everyday Health
Multiple Myeloma - Everything You Need To Know - Dr. Nabil Ebraheim
 
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Dr. Ebraheim’s educational animated video describes multiple myeloma. Multiple myeloma is cancer of the plasma cells. It is malignant proliferation of the plasma cells. Plasma cells are a type of blood cells that produce antibodies. Antibodies are an important part of the immune system that fights infection. Multiple myeloma cells produce a single protein – Monoclonal protein, M protein. Multiple myeloma occurs more often in males and twice as often in African Americans. It usually occurs in patients older than 40 years of age. Multiple myeloma is the most common primary malignant bone tumor. The plasma cells secrete osteoclast activating factors such as interleukin 6, macrophages and inflammatory factors in addition to RANKL. Osteoclasts are recruited, activated and they multiple. Osteoclasts absorb the bone. The osteoblast bone formation is suppressed by the tumor necrosis factor (why there is a cold bone scan in multiple myeloma). In about 30%, the bone scan is negative. Get a skeletal survey. Clinical features: Useful mnemonic to help remember the most common features of multiple myeloma is CRAP, which stands for hypercalcemia, Renal failure, Anemia, and back Pain. Clinical features will be insidious presentation. Bone pain, especially back pain with possible fractures, weakness and fatigue, cord compression, infections and fever. Multiple myeloma can occur in any bone although it occurs more in the hematopoietic bone marrow! Labs: Sedimentation rate may be elevated. May find renal insufficiency, hypercalcemia, and anemia. Electrophoresis will find a spike in the serum, in the urine, or in both. Serum Protein ElectroPhoresis (SPEP) detects monoclonal elevation of the immunoglobulin and identifies the protein types that are present. Urine Protein ElectroPhoresis (UPEP) – bence jones proteinuria (urine) and light chains (about 95% sensitivity). What are the tumor markers that indicate a bad prognosis? Increased serum beta1-microglobulin level and a decreased serum albumin. How do you establish the diagnosis? One major and one minor criteria is needed or three minor criterion. What are the major criteria? The major criteria are plasmacytoma tissue diagnosis on biopsy, more than 30% plasma cells in the bone marrow, SPEP with great value for IgG or IgA and/or UPEP (Bence Jones Proteinuria). The minor criteria are 10% - 30% plasma cells in the bone marrow, monoclonal protein in the serum or the urine (SPEP/UPEP – these values are usually lower than in the major criteria), multiple “punched-out” lytic bone lesions, end-organ damage (renal insufficiency, hypercalcemia, and anemia), and lower than normal IgG levels. Images: Images will usually show “punched-out” lytic lesions throughout the skeleton. Radiolucent lesions or destructive lesions with no sclerosis (skull lesions and vertebral fractures). Osteopenia is common. There will be a negative bone scan. Minimal osteoblastic activity with multiple myeloma due to the tumoral necrosis factor. Skeletal survey can be used. Sometimes a magnetic resonance imaging (MRI) or positron emission tomography (PET) scan may be used. Bone scans are generally not done in cases of multiple myeloma (bone scans will be cold). Pathology: Sheets of plasma cells, Eccentric nucleus (clock faced), Signet-ring appearance, Perinuclear clearing, Abundant eosinophilic cytoplasm. Treatment: Usually high-dose chemotherapy. Radiation treatment for progressive lesions, structurally important lesions, or radiation is used to decrease pain. Bone marrow transplant (usually in younger patients). Bisphosphonate decreases bone pain, calcium and the number of lesions. Surgical stabilization is used for prophylactic fixation or prevention of pathological fractures. It can also be used for the treatment of fractures. Become a friend on facebook: http://www.facebook.com/drebraheim Follow me on twitter: https://twitter.com/#!/DrEbraheim_UTMC Donate to the University of Toledo Foundation Department of Orthopaedic Surgery Endowed Chair Fund: https://www.utfoundation.org/foundation/home/Give_Online.aspx?sig=29
Просмотров: 35281 nabil ebraheim
Epidemic of Facial Pain from Bisphosphonates
 
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Dr. Joe talks about bisphosphonates being pulled off the market due to pain.
Просмотров: 461 Joe Prendergast
Carpal Tunnel Syndrome | bisphosphonates cause carpal tunnel syndrome
 
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https://www.arthritistreatmentcenter.com Here’s another complication of taking bisphosphonate drugs for osteoporosis… next Do Bisphosphonates Increase Risk of Carpal Tunnel Syndrome? Lara Pullen writing in the Rheumatologist reported increasingly, postmenopausal women are prescribed bisphosphonates in an effort to prevent osteoporotic fractures. The increased prevalence of bisphosphonate use likely reflects both demographic trends toward an older female population, as well as concerns about the safety of an alternative treatment for osteoporosis: hormone replacement therapy. Unfortunately, bisphosphonates are not without risk. In 2008, the FDA issued an alert that highlighted the association between oral bisphosphonates and incapacitating bone, joint and/or musculoskeletal pain. In 2015, the FDA issued yet another alert: warning that the use of bisphosphonates is associated with an increased risk for developing osteonecrosis of the jaw. Researchers have also noted that patients taking bisphosphonates experience an increased risk for arthritis and corresponding arthralgia. Now, investigators report that postmenopausal women who use bisphosphonates are also at increased risk for carpal tunnel syndrome. Comment: what a list of side effects. These drugs might be useful but be careful. https://youtu.be/_s--KEKg_3A
Просмотров: 99 Nathan Wei
Are bisphosphonates an effective treatment for early stage breast cancer?
 
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Professor Michael Gnant talks about supporting this particular adjuvant therapy and its benefits to the patient. Watch the full video here: http://ecancerpatient.org/video/45
Просмотров: 52 ecancer
Dr. Aft on Bisphosphonates for Breast Cancer
 
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Rebecca L. Aft, MD, PhD, Professor of Surgery at the Washington University School of Medicine in St. Louis and a physician at Siteman Cancer Center, discusses the use of bisphosphonates for patients with breast cancer. More on breast cancer: http://www.onclive.com/specialty/breast-cancer
Просмотров: 111 OncLiveTV
Osteonecrosis of Jaw
 
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Просмотров: 4671 Heath and Beauty
SABCS: More Evidence that Bisphosphonates Prevent Breast Cancer
 
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http://www.medpagetoday.com SAN ANTONIO -- Women taking the osteoporosis drug zoledronic acid had a 30% to 35% lower risk of breast cancer, according to data from two different retrospective studies. Medpage Today: http://medpagetoday.com Online CME - Continuing medical education: http://www.medpagetoday.com/cme/ Latest medical news: http://www.medpagetoday.com/latest/ The MedPage Today app: iOS: https://goo.gl/JKrkHq Android: https://play.google.com/store/apps/details?id=com.medpagetoday.medpage MedPage Today Youtube Channel: https://www.youtube.com/user/MedPageToday Medpage Today on Facebook: https://www.facebook.com/MedPageToday
Просмотров: 116 MedPage Today
How Safe are Bisphosphonates?
 
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The bisphosphonates are a well-known family of medications used to cure osteoporosis and atrial fibrillation. The following drugs are all in the bisphosphonate family: Fosamax, Actonel, Boniva, and Reclast. These medications are all very similar with some variations. Recently, these drugs have been reported to have caused severe health problems to its users. FDA is now undergoing thorough evaluation and investigation on these drugs. For more information, visit http:www.hummerlaw.com or you can also call at 1-800-433-8420.
Просмотров: 916 chuckrightontop
Which drug is more effective for the treatment of breast cancer: denosumab or bisphosphonates?
 
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Wolfgang Janni, MD, PhD, of the University of Ulm, Ulm, Germany, talks about his side of the debate of whether denosumab or bisphosphonate are more effective drugs for the treatment of breast cancer at the 2016 World Congress on Controversies in Breast Cancer (CoBrCa) in Barcelona, Spain. He explains that his role in the debate is to argue in favor of using denosumab instead of bisphosphonate. He believes that there is very convincing data comparing bisphosphonates and denosumab. Furthermore, the efficacy of denosumab in terms of preventing skeletal-related events, such as pain and also costs associated with with skeletal-related events is much better. He explains that although bisphosphonates have been a lot of help in the past, denosumab is the more effective treatment option now.
Просмотров: 59 VJOncology
MediaPharm - Breaking News Flash - Risk of Rare Fractures With Long-Term Bisphosphonate Use
 
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Recent findings have suggested that patients on bisphosphonate therapy for prevention of osteoporosis are at increased risk of a rare, painful and debilitating type of leg fracture. Are you or a loved one at risk? What is the warning sign that a fracture is pending? Join Dr Robert Savage for this podcast to find out.
Просмотров: 231 MediaPharm
Cancer: RANK Ligand Mechanism of bone metastasis
 
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This video describes the role of the RANK-RANK Ligand system in the process of cancer metastazing to the bone. Cette vidéo décrit le rôle du système RANK-RANK Ligand dans le processus de développement des métastases osseuses. Association website: http://www.efp-online.fr Online education: http://www.invivoveritas.fr
Просмотров: 17979 AssoEFP
What Bone Metastasis Looks Like
 
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be creativo Subscribe today and give the gift of knowledge to yourself or a friend What Bone Metastasis Looks Like 1 : What Is Bone Metastasis? 2 : Risk Factors 3 : Where Bone Metastases Form 4 : Symptoms 5 : Cord Compression 6 : How Metastasis Affects the Bones 7 : Imaging Tests for Bone Metastases 8 : Lab Tests for Bone Metastases 9 : Treating the Primary Cancer 10 : Bisphosphonates 11 : Treating Just the Bones 12 : Surgery 13 : Pain Management 14 : After Treatment
Просмотров: 194 Health & Medication
Hypercalcemia - causes, symptoms, diagnosis, treatment, pathology
 
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What is hypercalcemia? Hypercalcemia's a condition in which there are higher than normal levels of free ionized calcium in the blood. Find more videos at http://osms.it/more. Study better with Osmosis Prime. Retain more of what you’re learning, gain a deeper understanding of key concepts, and feel more prepared for your courses and exams. Sign up for a free trial at http://osms.it/more. Subscribe to our Youtube channel at http://osms.it/subscribe. Get early access to our upcoming video releases, practice questions, giveaways and more when you follow us on social: Facebook: http://osms.it/facebook Twitter: http://osms.it/twitter Instagram: http://osms.it/instagram Thank you to our Patreon supporters: Sumant Nanduri Omar Berrios Alex Wright Sabrina Wong Suzanne Peek Arfan Azam Mingli Féng Osmosis's Vision: Empowering the world’s caregivers with the best learning experience possible.
Просмотров: 111763 Osmosis
Bisphosphonates: For Healthy and Strong Bones?
 
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Bisphosphonates are prescribed to help keep the bones strong and healthy, consequently reducing the risk of osteoporosis. Are there risks on taking these kind of drugs? Are there serious side effects? For more information, visit http://www.hummerlaw.com or call Hummer Law Offices at 1-800-433-8420.
Просмотров: 160 chuckrightontop
How bisphosphonates interact with your bone crew
 
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Bisphosphonates long term are bone breakers not bone saviours http://www.betterbodychemistry.com/bones/bisphosphonates-bone-crew/ Bisphosphonates are the standard treatment for osteoporosis - initially they make a big difference, improving bone density but the benefit fades with time. Leave your questions or comments below ======================================= **Click below to SUBSCRIBE for More Videos http://www.youtube.com/subscription_center?add_user=spoonfulofscience ======================================= Dr Sandy Evans Scientist turned gremlin buster, helping your create BETTER BODY CHEMISTRY http://www.betterbodychemistry.com Facebook: http://www.facebook.com/betterbodychemistry/ Get the Free WILLPOWER REPORT http://upvir.al/5510/willpower-report
Просмотров: 25570 Better Body Chemistry TV
Attorney for necrosis jawbone death Fosamax & Boniva
 
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Story about General Hospital's Sharon Wyatt whom has to undergo major jawbone surgery for Jawbone necrosis, caused by use of bisphosphonates. Sharon had to have part of her dead jawbone cut out and removed. In it's place is a titanium plate, screwed into the surrounding jawbone. If you or a loved one has suffered serious side effects from taking Fosamax or Boniva, please call our office today at 727-397-9198 for a free consultation or visit us at http://www.hummerlaw.com
Просмотров: 217 hummerlaw
Fosamax Drug Injury Lawyer
 
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Fosamax is part of a class of drugs known as bisphosphonates, which are used to treat osteoporosis and bone pain caused by some types of cancer. Fosamax is the most commonly dispensed bisphosphonate in the United States and accounted for 22 million prescriptions by 2004 (2). Bisphosphonates are often used in the management of certain cancers—such as lung, breast, prostate, and multiple myeloma—where cancer has metastasized (spread) to the bone.
Просмотров: 1727 DrugLawyers
Dr. Julie Gralow on Treating Breast Cancer Bone Metastases
 
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Julie R. Gralow, MD, Director, Breast Medical Oncology, Seattle Cancer Care Alliance, discusses the recent changes occurring in the anti-osteoclastic targeted therapies used to treat breast cancer bone metastases. The bisphosphonates zoledronic acid (Zometa) and Pamidronate (Aredia) have traditionally been used to treat breast cancer bone metastases. These agents work by blocking the cells that cause bone destruction, which prevents the loss of bone mass. Recently the agent denosumab (Xgeva), a RANK-ligand inhibitor, has become available. In comparison trials, at new diagnosis, between denosumab and bisphosphonates, denosumab proved superior at reducing skeletal-related events and improving other quality of life measures. Gralow advocates for using denosumab in the first-line, when appropriate, or in the second-line after progression on zoledronic acid. Denosumab can be delivered subcutaneously with fewer concerns over serum creatinine levels or first infusion reactions. With the addition of new agents there are now multiple choices for metastatic breast cancer. Trials have now begun to investigate dosing schedules to optimize delivery. The OPTIMIZE-2 trial examined bisphosphonate dosing schedules to determine if they should be given monthly, or every 3 months. Providing therapy every 3 months would reduce many of the adverse events associated with the treatment, such as osteonecrosis of the jaw.
Просмотров: 2897 OncLiveTV
Winter Park Family Dental- Fosamax, Boniva, Reclast, Bisphosphonates
 
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Dr Ramzi Matar discusses current medical management of patients taking bisphosphonate medications for treatment of malignant cancers, post menopausal women. How to avoid "BRONJ" or "Jaw Death." You can reach us at www.winterparkfamilydental.com
Advances in prevention and treatment of bone metastases in prostate cancer
 
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Winston Tan, MD of Mayo Clinic, Jacksonville, FL discusses a treatment of bone metastases in prostate cancer. Dr Tan mentions that addition of bisphosphonates does not increase the overall survival of patients suffering from various cancer types, including breast cancer, prostate cancer, and renal cancer. Cabozantinib, approved for metastatic renal cancer makes the bone metastases disappear, however, it has not been shown to increase survival in patients with a metastatic prostate cancer in a phase III randomised clinical trial. A combination of two or three drugs may be required to achieve better results in patients. The next step would be to look at markers, a combination of targets and drugs which can work together to help improve survival and prevent the consequences of bone metastases. Dr Tan highlights the importance of supportive care for cancer patients, who can benefit from an access to physical therapists, psychologists, and nutritionists. This could mean less bone pain and decreased use of pain medication, which may cause dizziness, constipation, or reduced mobility. Ongoing studies in the metastatic prostate cancer compare the micro-environmental factors, before and after the treatment to better understand which genetic and metabolic factors affect the bone metastases. Dr Tan says that prostate cancer patients with bone pain should be offered Radium 223, which improves survival and long-term can improve the symptomatology, and bisphosphonates, or denosumab, which is known to prevent skeletal-related events. Recorded at the Multinational Association of Supportive Care in Cancer (MASCC) and International Society of Ocular Oncology (ISOO) 2016 Annual Meeting on Supportive Care in Cancer held in Adelaide, Australia.
Просмотров: 326 VJOncology
Treating Osteoporosis Caused by Hyperparathyroidism - Michael Yeh, MD | UCLA Health News
 
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For hyperparathyroidism, a leading cause of osteoporosis, drugs don’t work/Dr. Michael Yeh, associate professor of surgery and medicine One leading cause of the bone-loss disease osteoporosis is hyperparathyroidism, which can be treated by surgery or drugs. New research now shows that surgery leads to fewer fractures, while commonly used prescription drugs called bisphosphonates can actually increase the risk of fracture, worse than doing nothing at. Learn more at https://uclahealth.org/endocrinecenter
Просмотров: 1542 UCLA Health
Controversies regarding the use of bisphosphonates in fracture prevention
 
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As the population ages, the prevalence of osteoporosis increases with resultant increase in the risks of bone fractures. We are also referring more people for assessment of bone mineral density, thereby able to find asymptomatic persons with low bone mineral density. This brings the dilemma of whether to treat or not to treat and, if so, when to do so. Profs. Andrew Borg, Consultant Rheumatologist, clarifies the issues relating to the prophylactic use of bisphosphonates in post-menopausal osteoporotic women.
Просмотров: 317 TheSynapse
Bisphosphonates and Femoral Fractures
 
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http://www.melioguide.com/free-course Bisphospohnate use over an extended period can lead to increased risk of femoral shaft fractures in older women according to a recent study published in the Journal of the American Medical Association (JAMA). The study results are explained in this video.
Просмотров: 1471 Margaret Martin
What Is The Life Expectancy Of A Person With Multiple Myeloma?
 
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A person with smm may be prescribed bisphosphonates for symptoms of. On this page you will learn about how doctors describe myeloma's growth or spread. How to tell when mgus becomes myeloma life expectancy and future course of lingering how hard can someone exercise with myeloma? . Aggressive treatment can reverse acute renal failure in many cases but the prognosis dec 15, 2016 multiple myeloma describes when a person has several of these plasma stage iii, life expectancy is 29 months (2 years, everyday health experts answer your questions about. However, some people beat the odds and live 10 to 20 years or more multiple myeloma life expectancy may be based on prognostic information provided by lab tests. In multiple myeloma, cancer cells build up in bone marrow and take over the healthy blood. Jul 28, 2016 multiple myeloma is a cancer of the blood. Stage ii or iii multiple myeloma is characterized by an intermediate high amount of cancer in the body. Multiple myeloma features abnormal proliferation of plasma cells in the bone marrow, destructive lesions, and production when i was first diagnosed, data for a person with dialysis dependent kidney more information on survival rates life expectancy click here latest statistics uk health professionals. Why do people beat the average multiple myeloma life expectancy research a new lease on treatments are extending expectancies survival rate, causes & prognosis medicinenet. See data for sex, age, trends over time and more multiple myeloma (mm) is a malignant plasma cell disorder with potential have been shown to poor overall survival, an average life expectancy of 9 feb 20, 2013 in august 2010, i was diagnosed stage iii myeloma, expectancy, treatment, or facing stark altering challenge. Relapsed or relapsed refractory multiple myeloma jadpro. Multiple myeloma patients join the community today. Survival rates by stage for multiple myeloma. Some patients with cancer may want to know mar 11, 2014 the latest seer(surveillance, epidemiology, and end results) data for multiple myeloma was published in 2013 by national institute, average life expectancy remains at 4 years third year a row. Doctors may also look at median survival mar 15, 2016 four new drugs, and novel treatment combinations, are further extending life expectancy for patients with multiple myeloma overview. Multiple myeloma patients join the community todaymultiple stage 1 myelomacrowd. System (iss) is now used more commonly to classify multiple myeloma. Live with a disease for which there is no cure, and be better person in the process nov 30, 2010 hence, through this post i am going to discuss few points that help predict life expectancy of suffering from multiple myeloma severe renal failure threatening complication. Multiple myeloma is a form of bone marrow cancer. It develops in plasma cells, which are white blood cells that help fight infection. Multiple myeloma outlook, life expectancy, survival rates healthline health cancer multiple o
Просмотров: 439 sandy sandy
FillerSupplies - ACLASTA 5mg (100ml – 1 vial)
 
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ACLASTA 5mg is useful in treating high blood calcium levels caused due to cancer. It is a bisphosphonate. It functions by reducing the breakdown of bone. This decreases the amount of calcium that is released into the blood from bones as well as aids in lowering blood calcium level. ACLASTA is used to treats Paget’s disease and osteoporosis in postmenopausal women. ACLASTA contains zoledronic acid (sometimes called zoledronate). It belongs to a group of medicines called bisphosphonates. Zoledronic acid inhibits the release of calcium from bones. You can buy ACLASTA 5mg from FillerSupplies.com in the USA.
Просмотров: 46 Filler Supplies International company
Cancer and Its Effects On Bones
 
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Encouraging news to help cancer patients manage their bone health New Data Presented at the Annual San Antonio Breast Cancer Symposium Adam Brufsky, MD, one of the nations leading breast cancer oncologists and researchers. -Assistant Professor of Medicine, Associate Division Chief for the Division of Hematology/Oncology, University of Pittsburgh School of Medicine -Co-Director, Comprehensive Breast Cancer Center; Medical Director, Women's Cancer Center at Magee Womens Hospital/UPCI, Pittsburgh, PA Even following treatment, people diagnosed with cancer still face the risk that their cancer may spread, or metastasize, to another part of their body, most commonly their bones. These bone metastases break down the bone, often leading to painful complications that can affect patients quality of life. In addition, certain cancer therapies can also affect the integrity of the bones. Treatments such as aromatase inhibitors, a class of drugs used to help treat breast cancer patients can sometimes also lead to bone loss. Results from data presented at the recent San Antonio Breast Cancer Symposium demonstrates the advantages of treatment with bisphosphonates, which are used to treat bone complications associated with cancer, in helping to improve and maintain bone health. Data showed that the use of bisphosphonates taken in conjunction with an aromatase inhibitor following surgery may significantly reduce the risk of fracture. Physician Biography: Dr. Adam Brufsky Medical Oncology Adam M. Brufsky, MD, PhD, is currently Assistant Professor of Medicine at the University of Pittsburgh School of Medicine. He serves as Co-Director, Comprehensive Breast Cancer Center and Medical Director, Women's Cancer Center at the Magee Womens Hospital/UPCI, Pittsburgh, PA. He also serves as the Associate Division Chief for the Division of Hematology/Oncology within the University of Pittsburgh School of Medicine's Department of Medicine. He earned his MD and his PhD from the University of Connecticut School of Medicine in Farmington, CT, completed a residency at Brigham and Women's Hospital, Harvard Medical School, and a Fellowship at Dana-Farber Cancer Institute. Dr. Brufsky is board certified in Internal Medicine and Medical Oncology by the American Board of Internal Medicine. An active researcher, he has numerous abstracts and research articles in leading journals, and is Principal Investigator on a number of research grants funded by the National Institutes of Health, Susan G. Komen Foundation, and US Army Breast Cancer Research Program.
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No benefit for adjuvant ibandronate at 3 years in early breast cancer
 
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Prof Linn speaks with ecancertv at SABCS 2016 to discuss the impact of adjuvant bisphosphonate therapy on patients with early stage breast cancer, finding that there was no significant improvement through its addition after 3 years follow up. Weighing the slight trends of gastrointestinal side effects against lowered risk of bone metastases, Prof Linn considers if 3 years is an adequate follow up to see the full effects of added bisphosphonate therapy, and notes patient concerns over osteonecrosis of the jaw as a side effect of treatment.
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Prescription Drugs Cause Bone Breaking in Patients - NY Attorney Matthew McCauley
 
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http://www.yourlawyer.com/topics/overview/fosamax Attorney Matthew McCauley of Parker Waichman discusses how 3 major prescription drugs are causing patients to suffer fractures in their leg. For patients who suffer bone diseases like osteoporosis and osteopenia, doctors typically describe a class of drugs known as bisphosphonates. These drugs are manufactured to the public with the brand names of Fosamax, Actonel, and Boniva. Recent studies have shown that these drugs are being linked to femur fractures in patients. Not only are they femur fractures, but something known as "atypical" femur fractures. And what this means is that these breaks aren't being caused by the normal accident or trauma to a leg. Patients are fracturing their femurs doing the most normal of things like getting out of their car or stepping off a curb. One recent report stated that an astounding 82% of people who suffered this type of fracture had been prescribed one of these bisphosphonate drugs. More research and investigation is being done to confirm that these drugs are causing this type of harm and whether or not they should remain on the market. Watch this video now to learn more. To learn more about prescription drug laws, I encourage you to watch the video above and to explore our educational website at http://www.yourlawyer.com/topics/overview/fosamax. If you have legal questions, I want you to call me at (800) 800-9797. I welcome your call. Matthew McCauley Parker | Waichman LLP 6 Harbor Park Drive Port Washington, NY 11050 (800) 800-9797 http://yourlawyer.com
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LivingWellChiro-Health Update: Fosamax
 
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Health update for week of January 5th: Fosamax now causing jaw necrosis and cancer increase.
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Bone Booster May Cut Cancer Risk
 
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http://www.dailyrx.com/bisphosphonates-may-reduce-endometrial-cancer-risk-women A new study found that women who had taken bisphosphonates had a reduced rate of endometrial cancer.
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Cancer Treatment
 
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This video has information about all the main cancer treatments, including surgery, radiotherapy, chemotherapy, hormone therapy, biological therapies, bisphosphonates and bone marrow and stem cell transplants. There is also information about complementary and alternative therapies. ----------------------------------------------- Find This Video Helpful? Please click below to share my website with friends & family. For more information check out: Our Website: goo.gl/4i6ovK Our Facebook Page: goo.gl/Ynt1qg Our Youtube Channel: goo.gl/glWkzo
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Prostate Cancer: Diet
 
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read more on the link : Researchers from Canada have found that having a diet of red meat, organ meats, soft drink and bottled water increased the risk of getting prostate cancer. They compared the diets of 80 men with prostate cancer, and 334 healthy men, and the diet just described more than doubled the risk of developing prostate cancer. So what prostate diet can reduce the risk of prostate cancer? Swedish researchers examined the diet of 1499 men with prostate cancer and 1130 men who were healthy, and they published their findings in the Cancer Causes and Control journal. They found that eating foods rich in phytoestrogens decreased the risk of prostate cancer. Phytoestrogens are plant molecules that have a weak estrogenic effect. They are made converted in the intestines from plant precursors by bacteria as they digest food. They are taken up by the same parts of the body that process the hormone estrogen. Interestingly, one of the treatments for prostate cancer by doctors involves using estrogens to reduce the level of testosterone in men with advanced prostate cancer. It does this indirectly, through its effect on the hypothalamus, as less luteinizing hormone releasing hormone is produced by the hypothalamus. This means not as much luteinizing hormone is released by the body, which suppresses the production of testosterone. High doses of estrogens for men can lead to cardiovascular complications. But phytoestrogens obtained from diet, in less quantities than a drug, and with a milder effect to start with, should not pose a problem. And researchers don't yet know what exactly causes phytoestrogens to have such a protective effect, whether it is similar to that of the estrogen treatment for advanced prostate cancers. And they don't know which phytoestrogens are the most active. So what phytoestrogen foods could you include in a diet for a healthy prostate? Soy beans and nuts are a good source. Soy and nuts contain a type of phytoestrogen called isoflavones, whilst berries and seeds contain lignans. Foods could include peanuts, sunflower seeds, peanuts, and berries. The only possible concerns with soy is that a study in mice found that male mice that had a type of heart disease that people also have, suffered heart failure when fed a soy based diet. Whether this extrapolates to the human population is yet to be established. But it may be wise for those me who have this particular genetic heart condition, dilated cardiomyopathy, to be cautious about soy products in their diet. But for other men, soy products could be good news. A meta analysis, which is a study of related studies, published in the International Journal of Cancer, found that diets high in soy lowered men's risk of prostate cancer by 30%. Another important mineral to consider for men is zinc. Zinc is used by men's bodies to make some of the male hormones, and for general prostate health. A deficiency in zinc can lead to problems with the testicles, the prostate, and the health of the sperm. Foods that are great sources of zinc include seeds like pumpkin, sesame, and sunflower; nuts like almonds, brazil, cashews and walnuts; and foods like lettuce, oats and onions. Raw onion is particularly suggested by Paul Bedson, a natural therapist. He also suggests vegetable juice made of equal parts of beetroot, carrot, and cucumber in cases where the prostate gland is enlarged. Cranberry juice, a cup drunk three times a day, is also recommended in this case. prostate, prostrate, cancer, prostate cancer, diagnosing prostate cancer, symptoms of prostate cancer, information on prostate cancer, prostate cancer treatment, mens cancer, men's cancer, PSA, psa, therapy, hormone, symptoms, prostatectomy, brachytherapy, cryosurgery, metastatic, 3D conformal, information, diet, research, radiation, radiotherapy, prevention, screening, localised, support, surgery, awareness, treatment, advanced, donation, symptom, bracytherapy, prostatic, gleason, tookit, Tool Kit, gleason score, biopsy, psa test, prostate gland, prostate specific antigen, HIFU, hifu, bisphosphonates, cryotherapy, health professionals, charity, men, campaigning, fundraising, gland, helpline, prostate cancer publications, prostate cancer booklets, diagnosed, palliative radiotherapy, chemotherapy, continence, events, fundraise, campaign, specialist nurses, african caribbean, prostate cancer charity, prostate cancer symptoms, trus, prostate problems, prostate cancer awareness month, prostate biopsy, gleason grading, DRE, BPH, prostatitis, localised prostate cancer, locally advanced prostate cancer, advanced prostate cancer, active surveillance, hormone therapy, high dose rate brachytherapy, bisphosphonates, palliative radiotherapy, clinical trials, HIFU,Prostate cancer, PSA,prostate cancer, oncology, medical animation, health app, educational, prostate cancer animated video, prostate cancer information, prostate cancer video
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What Can Cause Osteonecrosis?
 
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Osteonecrosis is caused when the blood flow to bone osteonecrosis can also affect people for no known by impaired supply who drink alcohol in excess develop fatty 1 sep 2016 webmd explains symptoms and treatment of avascular necrosis this type injury bone, leading information on patients caregivers such as causes, getting cause severe pain disability, much like arthritis does 2 aug 2017 osteonecrosisischemic necrosisavn lead joint pain, especially hip. Osteonecrosis of the knee an overview hss. Also called osteonecrosis, avascular necrosis can lead to tiny breaks in the bone and bone's eventual collapse. What is osteonecrosis of the jaw? Osteogenesis imperfecta medication related jaw in patients with cancer. Pain osteonecrosis can affect any bone, but the hips, knees and jaws are most often involved of jaw (onj) has recently been reported in people receiving intravenous or oral bisphosphonate drugs for reasons other than oi. Treatment with systemic 3 feb 2017 osteonecrosis of the jaw (onj), which was first described in 2002, is a reasons for these differences could include Questions and answers about (avascular necrosis). Osteonecrosis of the hip orthoinfo aaos. Avascular necrosis get facts on symptoms and treatment. Questions and answers about osteonecrosis (avascular necrosis). Osteonecrosis american college of rheumatology. Osteonecrosis of the knee orthoinfo aaos. Osteonecrosis can also be caused by bone fractures that interrupt the necessary blood supply to aseptic necrosis (avascular or osteonecrosis) develops when trauma, damage vessels 9 dec 2015 avascular (aseptic is a death of bone, do not function normally, are weakened, and collapse because cells die without supply, osteonecrosis ultimately lead cause. Loss of blood supply to the bone can be caused by an injury (trauma related osteonecrosis or joint 9 may 2015 disease severe trauma, such as a fracture dislocation, that affects learn about causes, symptoms, diagnosis & treatment from this disorder occur spontaneously 16 apr 2013 disease, it is causes break down hip. The blood flow to a symptoms osteonecrosis has several causes. Osteonecrosis of the jaw wikipedia. The damage to the 21 mar 2015 avascular necrosis is death of bone tissue due a lack blood supply. Aseptic necrosis of the hip, femur and bone symptoms medicinenet. Avascular necrosis (osteonecrosis) treatment, causes, and moreosteonecrosis nord (national organization for rare disorders)osteonecrosis bone, joint, muscle disorders merck manuals osteonecrosis symptoms, diagnosis, treatment of cleveland clinic. They stop taking bisphosphonates, but the complications can linger. Hip osteonecrosis background, problem, epidemiology. Avascular necrosis (osteonecrosis) symptoms, treatment, and more. Osteonecrosis of the hip develops when blood supply to osteonecrosis knee can affect anyone, but is more common in people over overconsumption alcohol time cause fatty deposits form 24 feb 2010 however, there are other conditions besides os
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Side Effects of Prednisone - That You Should Be Aware Of Before Using ❗
 
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side effects of prednisone is used to treat conditions such as arthritis, blood disorders, breathing problems, severe allergies, skin diseases, cancer, eye problems, and immune system disorders. Prednisone long term side effects belongs to a class of drugs known as corticosteroids. It decreases your immune system's response to various diseases to reduce symptoms such as swelling and allergic-type reactions. Prednisone side effects in men may weaken your immune system. A weakened immune system makes you more likely to get infections. More common side effects The more common side effects that occur with prednisone side effects short term include: confusion excitement restlessness headache nausea vomiting thinning skin acne trouble sleeping weight gain severe allergic reactions changes in emotions or moods, such as depression changes in vision eye pain infection, with symptoms such as: fever or chills cough sore throat trouble or pain in passing urine high blood sugar, with symptoms such as: increased thirst passing urine more often feeling sleepy or confused swelling of your ankles or feet The most commonly reported adverse effects associated with corticosteroid use include fluid retention, alteration in glucose tolerance, high blood pressure, behavior and mood changes, increased appetite and weight gain. Side effects of prednisone and other corticosteroids range from mild annoyances to serious, irreversible organ damage, and they occur more frequently with higher doses and more prolonged treatment. Common side effects include: Retention of sodium (salt) and fluid Weight gain on prednisone High blood pressure Loss of potassium Headache Muscle weakness Nausea Vomiting Acne Thinning skin moon face Serious side effects include: Hiccups Puffiness of the face (moon face) Growth of facial hair Thinning and easy bruising of the skin Impaired wound healing Glaucoma Cataracts Ulcers in the stomach and duodenum Worsening of diabetes Irregular menses Rounding of the upper back ("buffalo hump") Obesity Retardation of growth in children Convulsions Anaphylaxis (severe allergic reactions like hives, itching, skin rash, swollen lips/tongue/face) Vision changes Congestive heart failure Heart attack Pulmonary edema Syncope Tachycardia Thrombophlebitis Vasculitis Allergic dermatitis Low blood pressure Amenorrhea (lack of menstruation) Newly onset diabetes Hyperglycemia Hypothyroidism Pancreatitis Anemia Amnesia This drug also causes psychiatric disturbances, which include: what is considered a high dose of prednisone Depression Euphoria Insomnia Mood swings Personality changes Psychotic behavior Other possible serious side effects of this drug include: Prednisone short term dosage and diabetes: is associated with new onset or manifestations of latent diabetes, and worsening of diabetes. Diabetics may require higher doses of diabetes medications while taking. Allergic reaction: Some people may develop a severe allergic reaction (anaphylaxis) to prednisone withdrawal after 5 days that includes swelling of the airways (angioedema) that may result in shortness of breath or airway blockage. Immune suppression: Prednisone 60 mg for 5 days side effects suppresses the immune system and, therefore, increases the frequency or severity of infections and decreases the effectiveness of vaccines and antibiotics. Osteoporosis: Prednisone may cause osteoporosis that results in fractures of bones. Patients taking long-term prednisone often receive supplements of calcium and vitamin D to counteract the effects on bones. Calcium and vitamin D probably are not enough, however, and treatment with bisphosphonates such as alendronate (Fosamax) and risedronate (Actonel) may be necessary. Calcitonin (Miacalcin) also is effective. The development of osteoporosis and the need for treatment can be monitored using bone density scans. Adrenal insufficiency and weaning off prednisone: Prolonged use of prednisone and other corticosteroids causes the adrenal glands to atrophy (shrink) and stop producing the body's natural corticosteroid, cortisol. tapering off prednisone after short term use Necrosis of hips and joints: A serious complication of long-term use of allergic reaction Prednisone is aseptic necrosis of the hip joints. Aseptic necrosis is a condition in which there is death and degeneration of the hip bone. It is a painful condition that ultimately can lead to the need for surgical replacement of the hip. Aseptic necrosis also has been reported in the knee joints. The estimated incidence of aseptic necrosis among long-term users of corticosteroids is 3%-4%. Patients taking corticosteroids who develop pain in the hips or knees should report the pain to their doctors promptly. Patient Advice Medical Disclaimer: It is always advised that Patients should check with their healthcare provider before starting any new medications, including herbal supplements and over the counter products, or receiving any vaccinations.
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FDA Urges Caution Over Long-Term Use of Bone-Density-Building Drugs
 
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Millions of women grapple with whether to take bone-density-building drugs to treat or prevent osteoporosis, but the FDA this week warned that long-term use of bisphosphonates can lead to rare fractures and side effects. Margaret Warner and Maine Medical Center's Dr. Clifford Rosen discuss the risks outlined by the FDA.
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Adjuvant Zoledronic Acid Reduces Breast Cancer Deaths
 
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Adding zoledronic acid to adjuvant endocrine therapy significantly improved disease-free and overall survival in premenopausal women with endocrine-receptor--positive early breast cancer at 7 years' follow-up in the Austrian Breast and Colorectal Cancer Study Group-12 trial. Dr. Michael Gnant describes the results in this interview at the San Antonio Breast Cancer Symposium.
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How to Build Bone Density without Bisphosphonates by Dr. Sangeeta Pati
 
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How to Build Bone Density without Bisphosphonates and the influence of nutrition, hormones, detox, mind and body
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Actos Diabetis Medication and Bladder Cancer
 
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After you have watched the short message on this video, please click on the link above to get more information about the risks of diabetes medication causing bladder cancer. http://leadtrx1.com/?a=514&c=591&s1= Bladder Cancer News Actos has become a growing bladder cancer lawsuit target. If you have taken Actos for the treatment of diabetes, your bladder cancer risks are likely to be much higher than they were before receiving the treatment. If when using Actos bladder cancer symptoms appear, a qualified Actos bladder cancer attorney may be able to get you the compensation you deserve. Actos Bladder Cancer Risk if you are a bladder cancer victim and have been taking Actos, Be sure to file your claim today. To Diabetes Patients Taking Actos For relevant info on bladder cancer, please, for your own benefit, if you have taken Actos for diabetes, please click on the link above to learn more about the possibility of an Actos bladder cancer settlement in your future. Actos side effects bladder cancer Actos and bladder cancer FDA bladder cancer actos bladder cancer from actos http://istecnews.com
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Clodronate Is An Absolute Must for Bone and Breast Cancer Patients - Fitnessential
 
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Clodronate Prevents Breast Cancer : http://www.Fitnessential.co/ Find out more about Clodronate Is An Absolute Must for Bone and Breast Cancer Patients Clodronate Prevents Breast Cancer The treatment of clodronate stops breast cancer from spreading to bone cancer. NOTE: Unavailable in United states. The meals FDA's suppression of clodronate has caused the needless death of around 30, 000 American women every year! Clodronate belongs to a band of drugs which are called bisphosphonates. Bisphosphonates are generally used in treating bone thinning (osteoporosis). In a few situations, they could protect your bones against a number of the ramifications of secondary cancer of the bones, such as for example pain and weakness. Secondary bone cancer occurs if the original (primary) cancer spreads to form a second cancer (metastasis) in the bone. Clodronate is often given alongside other cancer treatments. As well as getting used in some types of secondary bone cancer, it is often been shown to be effective in people who have myeloma (cancer of plasma cells in the blood). Additionally it is used to lower an increasing calcium levels in the blood. Because of secondary cancer of the bone, calcium, which helps fortify the bones, may be lost from the damaged bone and seep to the bloodstream. An increasing amount of calcium in the blood is recognized as hypercalcaemia. This may cause symptoms like for example feeling/being sick (nausea and/or vomiting), tiredness, irritability and even confusion. Clodronate might help reduce high degrees of calcium. Secondary cancer inside the bones may make them weak, and in some situations they might break (fracture). Clodronate might help restrengthen the bones and decrease the risk of fractures. Cancer can impact the bones in different ways, and clodronate isn't helpful for all cancers that affect the bones. Your doctor or specialist nurse can tell you if it would be helpful for you. In normal bone, two types of cells called osteoclasts and osteoblasts come together constantly to shape, rebuild and strengthen existing bone: osteoclasts which destroy old bone and osteoblasts which build new bone. Myeloma and some secondary bone cancers can produce chemicals that produce the osteoclasts work harder. Which means that more bone is destroyed than rebuilt, that leads to weakening of the affected bone. This may hurt and ensures that the bone can fracture or break easier. Clodronate targets areas of bone where the osteoclast activity is high. It helps bring the total amount of osteoclast and osteoblast activity back again to normal by reducing the experience of the osteoclasts. This may reduce pain and help fortify the bone. Additionally, it ensures that less calcium is likely to be lost from the bones. Clodronate is given as a tablet or capsule, frequently taken a couple of times each day. It is recommended that you just take the tablet or capsule in the morning and evening, and not within one or two hours of eating, having a milky drink or taking other medicines. It is because it's harder it to be absorbed to the bloodstream, which can make it much less effective. Avoid using clodronate with mineral supplements, such as for example multi-minerals, for the exact same reason. Read more about this on my blog at: http://www.fitnessential.co/blog/clodronate-stops-breast-cancer-in-its-tracks
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Potential Risks of Osteoporosis Medications
 
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MedStar NRH's Dr. Robert Bunning has conducted extensive research on how osteoporosis medications called bisphosphonates may cause sudden bone breaks and fractures. He provides insight on the subject in this piece that originally aired on Channel 4 News (NBC4) in Washington, DC. Learn more about Orthopaedic Injuries and Post-Surgical Services: http://ow.ly/OWe1i Learn more about Dr. Bunning: http://ow.ly/OWelL
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Attorney for femur bone fractures from bisphosphonates Fosamax Boniva
 
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Diane Sawyer interviews Dr. Richart Besser regarding the skyrocketing use of the Biophosphonate called Fosamax made by Merch. Taken long-term, Bisphosphonates can cause bones to become weak, brittle and even shear. Many women have reported breaks in their thigh bones. If you or a loved one has suffered serious side effects from taking Fosamax or Boniva, please call our office today at 727-397-9198 for a free consultation or visit us at http://www.hummerlaw.com
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