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Penicillin Allergy Skin Testing with PRE-PEN® for Allergists
Click the link below to view package insert: http://www.pre-pen.com/files/PREPEN_Package_Insert.pdf
Просмотров: 19209 ALKAbelloUS
Medical Mythbusters - Penicillin Allergy Cross-Reactivity
Cottage Health medical resident, Samantha Mathews, MD, explores the long held belief that patients who are allergic to Penicillin should avoid Cephalosporins and Carbapenems as well. What do you think? Join the discussion and let us know if you think this Medical Myth is confirmed, plausible, or busted in the comments section.
Просмотров: 881 Cottage Health
If I Have A Penicillin Allergy Does That Mean I Will Be Allergic to Other Antibiotics?
For more information visit http://www.rxwiki.com/ Up to 10 percent of people report being allergic to penicillin or the penicillin class of antibiotics, making it the most commonly reported drug allergy. If you are allergic to penicillin, it’s recommended to avoid medicines in the same antibiotic class such as amoxicillin and ampicillin. Certain antibiotics that should be used with caution in penicillin allergic patients include drugs in the cephalosporin class such as cephalexin (Keflex). Cephalosporins have a low rate of causing an allergic reaction in people who are allergic to penicillin, but their use should still be monitored in these people. Remember, just because you show allergic symptoms after taking penicillin doesn’t mean that you will react to related drugs, such as amoxicillin, but it increases the chances that you might. Also, just because you had a reaction to penicillin (or any other drug) at one point doesn’t mean you will have the same reaction later on. The best decision is to always watch for signs of an allergic reaction such as a rash, hives, or trouble breathing. Make sure to contact your doctor if you have signs of an allergic reaction and seek medical care if you have difficulty breathing. Always let your pharmacist and doctor know if you have a penicillin allergy.
Просмотров: 3975 RxWikiTV
Cephalosporins - Antibiotics Explained Clearly
Dr. Roger Seheult of http://www.medcram.com illustrates the key differences and coverage between the various types and generations of cephalosporin antibiotic medications: 0:24 - The five generations of cephalosporins. 0:50 - 1st generation of cephalosporins (cefazolin, cephalexin) and coverage. 2:10 - 2nd generation cephalosporins (cefuroxime, cefotetan). 3:11 - 3rd generation cephalosporins (ceftriaxone, cefotaxime, ceftazidime). 5:28 - 4th generation cephalosporins (cefepime). 6:57 - 5th generation cephalosporins (ceftolozane/tazobactam, ceftaroline). 10:00 - Combining an extended spectrum beta lactamase. 10:20 - Review of cephalosporin generations and cephalosporin coverage. To access the full library of MedCram videos, quizzes, courses and review notes, please visit: http://www.medcram.com Speaker: Roger Seheult, MD Clinical and Exam Preparation Instructor Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine. MedCram: Medical topics explained clearly including: Asthma, COPD, Acute Renal Failure, Mechanical Ventilation, Oxygen Hemoglobin Dissociation Curve, Hypertension, Shock, Diabetic Ketoacidosis (DKA), Medical Acid Base, VQ Mismatch, Hyponatremia, Liver Function Tests, Pulmonary Function Tests (PFTs), Adrenal Gland, Pneumonia Treatment, any many others. New topics are often added weekly- please subscribe to help support MedCram and become notified when new videos have been uploaded. Subscribe: https://www.youtube.com/subscription_... Recommended Audience: Health care professionals and medical students: including physicians, nurse practitioners, physician assistants, nurses, respiratory therapists, EMT and paramedics, and many others. Review for USMLE, MCAT, PANCE, NCLEX, NAPLEX, NDBE, RN, RT, MD, DO, PA, NP school and board examinations. More from MedCram: Complete Video library: https://www.youtube.com/c/medcram Facebook: https://www.facebook.com/MedCram Google+: https://plus.google.com/u/1/+Medcram Twitter: https://twitter.com/MedCramVideos Produced by Kyle Allred PA-C Please note: MedCram medical videos, medical lectures, medical illustrations, and medical animations are for medical educational and exam preparation purposes, and not intended to replace recommendations by your health care provider.
Просмотров: 120922 MedCram - Medical Lectures Explained CLEARLY
Penicillin Allergy Skin Testing with PRE-PEN® for Hospitals
Click the link below to view package insert: http://www.pre-pen.com/files/PREPEN_Package_Insert.pdf
Просмотров: 8595 ALKAbelloUS
Cephalosporin  Use in Treatment of Patients With Penicillin Allergies
Michael Marcus MD Pediatric Pulmonology and Allergy/Immunology
Просмотров: 967 drmdk
Penicillin allergic reactions
Unit 4 Video 10 Chapter 14 This video covers the different types of hypersensitivities that can occur to penicillin.
Просмотров: 1412 Joe DeMasi
-lactam allergy: The True Clinical Implication - Queenet Ibekweh, PharmD
Queenet Ibekweh, PharmD, speaks about the clinical implications of beta-lactam antibiotic (penicillin, carbapenem and cephalosporin) allergies. She discusses the different pathways of hypersensitivity reactions, cross-reactivity, epidemiology, pathophysiology, diagnosis, and management of penicillin induced adverse drug reactions. She also discusses the use of beta-lactam antibiotics in patients with documented penicillin allergies. IDPodcasts brings you essential updates in medical infectious diseases learning, brought to you from the University of South Florida’s Division of Infectious Disease. Stay in touch! Download our app on the Itunes store or find us below: Subscribe to our Youtube Channel: https://www.youtube.com/user/IDPodcasts Visit us on our webpage: http://www.idpodcasts.net/USF_ID_Podcasts/Main/Main.html Follow and like us on Facebook: https://www.facebook.com/ID-Podcasts-216965201680987/ Tweet to us: https://twitter.com/idpodcasts
Просмотров: 885 IDPodcasts
Penicillins - Antibiotics Explained Clearly
Dr. Roger Seheult of http://www.medcram.com illustrates the key differences between the various types of penicillin antibiotic medications: 0:57 - Discovery and brief history of penicillin 1:44 - Penicillinase 2:00 - Semi-synthetic penicillins (methicillin, oxacillin, nafcillin) 3:21 - Need for gram negative antibiotic coverage (E-coli, pseudomonas, etc.) 4:26 - Aminopenicillins (ampicillin, amoxicillin) 4:49 - Extended spectrum penicillin (piperacillin, ticarcillin) 5:14 - Beta-lactamase 5:42 - Beta-lactamase inhibitors (ampicillin/sulbactam and amoxicillin/clavulanic acid 6:35 - Piperacillin/tazobactam 6:54 - Ticarcillin and clavulanate 8:18 - Staph aureus and mutations against penicillin (PCN) 8:42 - MRSA - methicillin-resistant staphylococcus aureus 9:14 - Clindamycin, trimethoprim and sulfamethoxazole, quinolones, vancomycin, daptomycin, and linezolid 10:13 - A note about cross-reactivity / low platelets 10:33 - MSSA and nafcillin Speaker: Roger Seheult, MD Clinical and Exam Preparation Instructor Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine. MedCram: Medical topics explained clearly including: Asthma, COPD, Acute Renal Failure, Mechanical Ventilation, Oxygen Hemoglobin Dissociation Curve, Hypertension, Shock, Diabetic Ketoacidosis (DKA), Medical Acid Base, VQ Mismatch, Hyponatremia, Liver Function Tests, Pulmonary Function Tests (PFTs), Adrenal Gland, Pneumonia Treatment, any many others. New topics are often added weekly- please subscribe to help support MedCram and become notified when new videos have been uploaded. Subscribe: https://www.youtube.com/subscription_... Recommended Audience: Health care professionals and medical students: including physicians, nurse practitioners, physician assistants, nurses, respiratory therapists, EMT and paramedics, and many others. Review for USMLE, MCAT, PANCE, NCLEX, NAPLEX, NDBE, RN, RT, MD, DO, PA, NP school and board examinations. More from MedCram: Complete Video library: https://www.youtube.com/c/medcram Facebook: https://www.facebook.com/MedCram Google+: https://plus.google.com/u/1/+Medcram Twitter: https://twitter.com/MedCramVideos Produced by Kyle Allred PA-C Please note: MedCram medical videos, medical lectures, medical illustrations, and medical animations are for medical educational and exam preparation purposes, and not intended to replace recommendations by your health care provider.
Просмотров: 153349 MedCram - Medical Lectures Explained CLEARLY
ß-Lactams: Mechanisms of Action and Resistance
Developed and produced by http://www.MechanismsinMedicine.com Animation Description: This animation starts with the explanation of bacterial cell wall synthesis, the process targeted by ß-Lactams. Structurally, most bacteria consist of a cell membrane surrounded by a cell wall and, for some bacteria, an additional outer layer. Internal to the cell membrane is the cytoplasm which contains ribosomes, a nuclear region and in some cases granules and/or vesicles. Depending on the bacterial species, a number of different external structures may be found such as a capsule, flagella and pili. In gram negative bacteria, the gap between the cell membrane and the cell wall is known as the periplasmic space. Most gram positive bacteria do not possess a periplasmic space but have only periplasm where metabolic digestion occurs and new cell peptidoglycan is attached. Peptidoglycan, the most important component of the cell wall, is a polymer made of N-acetyl muramic acid alternating with N-acetyl glucosamine which are cross-linked by chains of four amino acids. The function of the bacterial cell wall is to maintain the characteristic shape of the organism and to prevent the bacterium from bursting when fluid flows into the organism by osmosis. Synthesis of peptidoglycan and ultimately the bacterial cell wall occurs in a number of stages. One of the first stages is the addition of 5 amino acids to N-acetyl muramic acid. Next, N-acetyl glucosamine is added to the N-acetyl muramic acid to form a precursor of peptidoglycan. This peptidoglycan precursor is then transported across the cell membrane to a cell wall acceptor in the periplasm. Once in the periplasm, the peptidoglycan precursors bind to cell wall acceptors, and undergo extensive crosslinking. Two major enzymes are involved in crosslinking: transpeptidase and D-alanyl carboxypeptidase. These enzymes are also known as penicillin binding proteins because of their ability to bind penicillins and cephalosporins. Eventually, several layers of peptidoglycan are formed all of which are crosslinked to create the cell wall. Gram positive bacteria have many more layers than gram negative bacteria and thus have a much thicker cell wall. Beta-lactam antibiotics include all penicillins and cephalosporins that contain a chemical structure called a beta-lactam ring. This structure is capable of binding to the enzymes that cross-link peptidoglycans. Beta-lactams interfere with cross-linking by binding to transpeptidase and D-alanyl carboxypeptidase enzymes, thus preventing bacterial cell wall synthesis. By inhibiting cell wall synthesis, the bacterial cell is damaged. Gram positive bacteria have a high internal osmotic pressure. Without a normal, rigid cell wall, these cells burst when subjected to the low osmotic pressure of their surrounding environment. As well, the antibiotic-penicillin binding protein complex stimulates the release of autolysins that are capable of digesting the existing cell wall. Beta-lactam antibiotics are therefore considered bactericidal agents. Bacterial resistance to beta-lactam antibiotics may be acquired by several routes. One of the most important mechanisms is through a process known as transformation. During transformation, chromosomal genes are transferred from one bacterium to another. When a bacterium containing a resistance gene dies, naked DNA is released into the surrounding environment. If a bacterium of sufficient similarity to the dead one is in the vicinity, it will be able to uptake the naked DNA containing the resistance gene. Once inside the bacterium, the resistance gene may be transferred from the naked DNA to the chromosome of the host bacteria by a process known as homologous transformation. Over time, the bacterium may acquire enough of these resistance genes to result in a remodelling of the segment of the host DNA. If this remodelled DNA segment codes for cross-linking enzymes (i.e. penicillin binding proteins), the result is the production of altered penicillin binding proteins. These altered penicillin binding proteins can still cross-link the peptidoglycan layers of the cell wall but have a reduced affinity for beta-lactam antibiotics thus rendering the bacterium resistant to the effects of penicillin and other beta-lactam agents. This transfer process has resulted in penicillin-resistant S. pneumoniae through the acquisition of genes from other naturally occurring penicillin-resistant Streptococcus species. A second important mechanism by which bacteria become resistant to beta-lactam antibiotics is by the production of enzymes capable of inactivating or modifying the drug before it has a chance to exert its effect on the bacteria. View animation to read more.
Просмотров: 717102 Mechanisms in Medicine
Allergy Testing Step 1, Skin Prick Testing
This video shows the actual steps utilized in initial skin testing for allergies. Those demonstrated in the video are a physician and the allergy staff at Northwest ENT and Allergy Associates with offices in Marietta, Woodstock, and Canton, Georgia.
Просмотров: 132324 NorthwestENT
3 Errors Causing AntiBiotic Allergy & Stevens-Johnson Syndrome
Doctor Jesse Garcia is interviewed by Drug Error Attorney Matt Hamilton. Antibiotic Allergy is explained in detail. Three medical drug mistakes that cause Stevens-Johnson Syndrome & Anaphylaxis are discussed. Toxic Epidermal Necrolysis, as the more acute version of Steven's-Johnson Syndrome is mentioned. Detailed Stevens Johnson Syndrome Medication Errors information is provided at: https://www.law-kc.com/drug-errors/stevens-johnson-syndrome/
Просмотров: 3305 Hamilton & Associates, Lawyers
CIDRAP ASP - Penicillin Allergy testing and Antibiotic stewardship (Sep 27th 2017)
CIDRAP-ASP hosted Dr. Kristin Alvarez, Dr. Wenjing Wei, and Dr. David Khan, as they presented “Penicillin Allergy testing and Antibiotic stewardship”.
Просмотров: 480 CIDRAPASP
Penicillin symptoms
via YouTube Capture
Просмотров: 212 ashley spafford
Erthyrthromycin for penicillin allergies (MACROLIDE)
via YouTube Capture
Просмотров: 218 Med School Radio
VANCOMYCIN - What You Need to Know
VANCOMYCIN - What You Need to Know Vancomycin is a bactericidal glycoprotein that binds to the d-Ala-d-Ala terminal of the nascent peptidoglycan pentapeptide side chain and inhibits transglycosylation. Vancomycin is indicated for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci. It is indicated for penicillin-allergic patients, for patients who cannot receive or who have failed to respond to other drugs, including the penicillins or cephalosporins, and for infections caused by vancomycin-susceptible organisms that are resistant to other antimicrobial drugs. Vancomycin is indicated for initial therapy when methicillin-resistant staphylococci are suspected, but after susceptibility data are available, therapy should be adjusted accordingly. Vancomycin is effective in the treatment of staphylococcal endocarditis. Its effectiveness has been documented in other infections due to staphylococci, including septicemia, bone infections, lower respiratory tract infections, skin and skin structure infections. When staphylococcal infections are localized and purulent, antibiotics are used as adjuncts to appropriate surgical measures. Vancomycin has been reported to be effective alone or in combination with an aminoglycoside for endocarditis caused by Streptococcus viridans or S. bovis. For endocarditis caused by enterococci (e.g., E. faecalis), vancomycin has been reported to be effective only in combination with an aminoglycoside. Vancomycin has been reported to be effective for the treatment of diphtheroid endocarditis. Vancomycin has been used successfully in combination with either rifampin, an aminoglycoside, or both in early-onset prosthetic valve endocarditis caused by S. epidermidis or diphtheroids. Specimens for bacteriologic cultures should be obtained in order to isolate and identify causative organisms and to determine their susceptibilities to vancomycin. To reduce the development of drug-resistant bacteria and maintain the effectiveness of vancomycin and other antibacterial drugs, vancomycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. VANCOMYCIN Mechanism of Action Vancomycin is an antibiotic drug which is structurally classified as a glycopeptide. It mainly acts by prevention of cell-wall biosynthesis of bacteria. It is specially effective against gram-positive bacteria and has been known to be effective against resistant strains of MRSA. Vancomycin is known as the drug of last resort as it generally used when all other treatments have failed. However, bacteria have started developing resistance to vancomycin as well- leading to use of other antibiotics. Vancomycin acts by inhibiting cell wall synthesis of bacteria. Peptidoglycan layer of the cell wall is rigid due to its highly cross-linked structure. During the synthesis of the peptidoglycan layer of bacteria, new building blocks of peptidoglycan get inserted (i.e. monomers of N-acetylmuramic acid and N-acetylglucosamine) into the membrane.Vancomycin inhibit the synthesis of bacterial cell wall phospholipids as well as peptidoglycan polymerization in a time dependent fashion by binding to the D-ala-D-ala side chain of the precursor pentapeptide.This prevent the transglycosylation step in peptidoglycan polymerization . By doing so, vancomycin makes the peptidoglycan layer less rigid and more permeable. This causes cellular contents of the bacteria to leak out and eventually death of the bacteria. Mutations in the transpeptidase enzyme can lead to increased resistance to vancomycin. Adverse Effects more than 10% Bitter taste (PO) Erythematous rash on face and upper body (IV; red neck or red man syndrome; related to infusion rate) Hypotension accompanied by flushing (IV) Nausea and vomiting (PO) 1-10% Chills (IV) Drug fever (IV) Eosinophilia (IV) Rash (IV) Fatique (PO) Peripheral edema (PO) Urinary tract infection (PO) Back pain (PO) Headache (PO) Reversible neutropenia (IV) Phlebitis (IV) less than 1% Nephrotoxicity Ototoxicity (especially with large doses) Stevens-Johnson syndrome Thrombocytopenia Vasculitis
Просмотров: 14307 Medinaz
Non beta lactam antibiotics and penicillin allergy - Choosing Wisely
Click here to find out more about penicillin allergy: https://www.aaaai.org/conditions-and-treatments/library/allergy-library/penicillin-allergy.
Просмотров: 914 4AI4YOU
Think you're allergic to penicillin? Get tested by an allergist
You may have been told at some point that you're allergic to penicillin. It may even be in your medical chart. But it's important to be tested by an allergist to find out for sure
This video is for educational purposes only. I am a 31 year old woman and just found out that I have an allergy to PENICILLIN. There was Penicillin my some medication I was recently prescribed my my doctor. After two days of taking this medication, I started to get very swollen eyes and an incredibly itchy rash broke out. Several days after changing medications, the rash has spread across my entire body. The itch is intense and I am not able to find much relief. I hope this video helps you. My doctor said that I have to be patient and simply let the penicillin leave my body...it is taking a while!!! Make sure you ask you doctor what is in your medicine before taking it.
Просмотров: 1147 Eve & Artie
Evidence Based Approach to Penicillin Allergy Assessment
Просмотров: 125 WombwellE
Allergic Reaction to Penicillin Medical Course
For Educational Use Only - Fair Use - Learn about alternative medicines that can be used if a patient has an allergic reaction to penicillin-based antibiotics.
Просмотров: 5528 Abagtha Abana
Antibiotic, Anti infective pharmacology Memory Tricks, Penicillin, Vancomycin, Gentamicin, Cefriaxon
Antibiotic, Anti infective pharmacology Memory Tricks, Penicillin, Vancomycin, Gentamicin, Cefriaxon Endocarditis antibiotics, like most antibiotics, work by binding to the bacterial cell wall, ultimately destroying and killing the organism. The infection then explodes like a grenade because the walls have broken down and collapsed. For more videos similar to this check out http://simplenursing.com/free-trial. Antibiotics Used The main antibiotics used for infective endocarditis are the following: • Penicillin • Vancomycin • Gentamycin • Ceftriaxone For every antibiotic, there’s a side effect. What are these side effects that are commonly tested in the NCLEX? For those patients who are allergic to penicillin, vancomycin is given. However, vancomycin is notorious for the Red Man Syndrome, which usually comes out when the drug is given too fast or if it’s given as the first dose. So, what is the Red Man Syndrome? And if this syndrome suddenly appears, what should the nurse do? Study the fun and fast way, while retaining more and grasping key concepts to get more prepared for your NCLEX & Exams. Sign up for a free trial at http://simplenursing.com/free-trial. Surgery If the disease has destroyed too much of any heart valve, surgery is the most viable solution. Surgery done for endocarditis can either be a replacement or repair. Patient Education Endocarditis patient education loves to show up on the NCLEX so you have to take note of them. We’ve made the acronym, M-O-L-D. What does MOLD stand for? Click on the video to find out. To access your free quiz and preview our nifty, new study guides that are not available on YouTube. The link is available above and here below. You can click it anytime during the video. FREE TRIAL: https://simplenursing.com/freetrialreg/ NCLEX FREE TRIAL: https://simplenursing.com/freetrialnclex/ Quiz & more videos Over 1,200+ Videos 80% NOT on Youtube Helping Over 60,000 Nursing Students 82% or Higher Test Average from our Users SUBSCRIBE TO OUR CHANNEL! https://www.youtube.com/simplenursing/subscribe Check out other videos: http://youtube.com/simplenursing Visit our social media sites: https://www.facebook.com/SimpleNursing/ https://www.instagram.com/simplenursing.com_/ https://twitter.com/simplenursing Our Popular Playlists: Respiratory FAILURE & Ventilators https://www.youtube.com/playlist?list=PL3NAm8UHLUnKFizmW0o-B44SS6YBzNErN Fluid & Electrolytes: https://youtu.be/OQSfIN2kvW8 Nursing Interview tips https://www.youtube.com/playlist?list=PL3NAm8UHLUnLEracDXCbIZkLeHqMcyP41 Over 1,200+ Videos – http://simplenursing.com/products/ 80% NOT on Youtube Simplenursing.com Official website Over 60,000 Nursing Students Helped 82% or Higher Test Average from our Users Go to: http://SimpleNursing.com - Lab Card - ABGs - EKGs - Fluid & Electrolytes FREE - Pharmacology FREE - Cardiac Pathophysiology - PATHO BIBLE "70 Care Plans Done-For-You" Please visit: https://simplenursing.com/products/ for more details on what is included with our memberships. Un-lock the mysteries of how simple nursing school can be.
Просмотров: 1999 Simple Nursing
HERE'S A SEXY PHOTO OF IT: http://www.facebook.com/photo.php?fbid=255910427778230&set=a.177173202318620.29637.170129773022963&type=1&theater
Просмотров: 42666 Leadley
Drug allergy: Do you really have a penicillin allergy?
This is a 2 minute tea with TP (Dr. Teresa Pun) for all of you out there with a history of a penicillin allergy. The vast majority people with a history of a penicillin allergy actulaly do not have an IgE mediated life threatening penicillin allergy upon testing. So, get tested :)
Просмотров: 88 Teresa Pun
Allergic to Penicillin
So it turns out that I'm allergic to Penicillin. I have strep, so I needed to go to the hospital to get another prescription. I wound up being prescribed Clindamycine (Teva-Clindamycine to be exact).
Просмотров: 1170 Davison (DavisonVideo)
"I'm Allergic to Penicillin"
Dr. Jeremy Price gives a brief talk on purported penicillin allergies (1/17/2018)
Просмотров: 232 Jacobi/Montefiore Emergency Medicine
You might think you have a penicillin allergy, but a simple skin test could prove you wrong
Просмотров: 196 Ivanhoe Web
Penicillin mechanism of action_in hindi||#Ep-12//03112018
Penicillin production by fermentation, Penicillin injection pain, cephalosporin, benzathine penicillin, allergic to penicillin, Antibiotics and pharmacology: penicillins explained clearly, Penicillin in hindi, Penicillin production by fermentation, Penicillin mechanism of action, Penicillin pharmacology, Penicillin dr najeeb For more video visit my youtube channel.. And for any information.. Visit my facebook gorup... https://youtu.be/55t79YNDAC8 Indian pharmatech Thanks for watching...
Просмотров: 134 Indian Pharmatech
Did You Know - The Truth About Penicillin Allergies
A new study by the American College of Allergy, Asthma and Immunology says at least 90% of those labeled with penicillin allergies have grown out of it or were misdiagnosed in the first place. For more information visit http://www.dailyrxnews.com/
Просмотров: 251 dailyRx
Anaphylaxis due to Drug allergy
http://www.amazon.com/dp/1451150237/ref=as_li_ss_til?tag=lifeisbettewi-20&camp=0&creative=0&linkCode=as4&creativeASIN=1451150237&adid=1P28WAQYWS6RNAX8PTEG http://www.medicalbook.org/t51-atopic-dermatitis-in-emergency-medicine Drug allergy unwanted side effect to certain medication.Food allergy same like Drug Allergy in effect,commonly skin reaction (rash).nousea ,vomiting, Diarrhea and swelling In mouth and throat. Drug allergy commonly occured secand time use of the medicine not first use. Drug allergy is ife-threatening conditin but rare to couse Death. You can learn more if you follow our youtube channel and follow our blog (Video for Doctors and Medical students) to see more updated videos.join us in: www.medicalvideofree.blogspot.com If you interested you can Read this topic: http://life4u.ahlamontada.com/t51-atopic-dermatitis-in-emergency-medicine
Просмотров: 5208 sheto sheto
Can you take cephalexin if you are allergic to penicillin
Can you take cephalexin if you are allergic to penicillin - Find out more explanation for : 'Can you take cephalexin if you are allergic to penicillin' only from this channel. Information Source: google
Просмотров: 19 moibrad5a
Penicillin Allergy or Not ?
Michael Marcus MD Pediatric Pulmonology and Allergy/Immunology Fellowship : Children's Hospital of Philadelphia
Просмотров: 1352 drmdk
Important Side Effects and Toxicities (Antibiotics - Lecture 8)
A lecture covering the major side effects of antibiotics, including allergic reactions, diarrhea, C.diff colitis, QT prolongation, and interactions with warfarin. It also includes discussion of cross reactivity between penicillins and cephalosporins, as well as how to use serum drug levels to titrate vancomycin and aminoglycosides.
Просмотров: 42651 Strong Medicine
How to recognize, respond to drug allergies
An allergic reaction to a drug can be very serious and potentially deadly, but some people don't know how to recognize one or what to do if they have one. Lisa Robinson reports.
Просмотров: 747 WBAL-TV 11 Baltimore
Introduction of Cephalosporin
Group B-Cephalosporin
Просмотров: 1113 namiir lafa
How Penicillin Changed The World
It is 90 years since a discovery was made that changed the world - penicillin. Since being accidentally discovered by Scottish scientist Alexander Fleming in 1928, the antibiotic has been used to save countless lives. Subscribe on YouTube: https://bit.ly/2JjpnIb - - - - - - - - - - - - - Facebook: https://www.facebook.com/Newsweek Twitter: https://twitter.com/Newsweek Instagram: https://www.instagram.com/Newsweek
Просмотров: 204 Newsweek
Are you really allergic to antibiotics? Doctors warn of allergy misconceptions
If you've ever been told you were allergic to penicillin and other antibiotics, doctors are now saying that's probably not the case.
Просмотров: 789 ABC 33/40
How antibiotics work , Part 2 - Everything You Need To Know - Dr. Nabil Ebraheim
Dr. Ebraheim’s educational animated video describes how the antibiotic works. •Cell wall: 1.Penicillins 2.Cephalosporins 3.vancomycin Inhibit the cell wall synthesis by blocking the cross-linking. The penicillin-binding protein enzymes are involved in the cross-linking. Beta-lactams have a ring that binds to the enzyme and prevents the cell wall synthesis. When beta-lactam inhibits the cell wall synthesis, this will cause damage to the bacterial cell. If you are allergic to penicillin or cephalosporins, you may be given clindamycin or vancomycin. Vancomycin may be given if methicillin-resistant Staphylococcus aureus (MRSA) is suspected or encountered (vancomycin is essential in the treatment of MRSA). Patients allergic to clindamycin may be given Cipro. The penicillin-binding protein is involved. mecA gene allows a bacterium to be resistant to antibiotics. This is how MRSA develops. The bacteria produce an altered penicillin-binding protein that can do the cross-linking but has no affinity to Beta-lactam antibiotics. It renders the bacteria resistant to the effects of penicillin and cephalosporins. Vancomycin is used in these cases. The transformation from one bacteria to another. Plasmid. Three main mechanisms by which resistant genes can be transferred: 1.Conjugation: the bacteria may conjugate their DNA from one bacteria to the other through transformation via a sex pilus. 2.Transformation 3.Transduction There is another mechanism which produces an enzyme that will inactivate the drugs before it reaches the bacteria. This is beta-lactamase which is capable of destroying the beta-lactam antibiotics. The bata-lactam ring of the antibiotics is destroyed and will not be able to bind to the wall. •Cell membrane: polymyxin. Polymyxin will increase the cell wall permeability. •Folic acid synthesis: sulfonamides, trimethoprim. •Nucleic acid synthesis: •DNA synthesis inhibitors: 1- Fluoroquinolones: ciprofloxacin (gyrase). DNA gyrase is responsible for removing the superhelical twist so that DNA replication can proceed. The fluoroquinolones inhibit the DNA gyrase. Using cirpo may contribute to the condition of Achilles tendon rupture. 2- Metronidazole (direct effect on DNA). Bacteriocidal that creates free oxygen radicals that are metabolic bi-products which disrupt the DNA. Can be used to treat pseudomembranous colitis c.diff. RNA polymerase inhibitors: rifampin. RNA polymerase is an enzyme that produces messenger RNA. The synthesis of messenger RNA is called transcription. Messenger RNA is DNA dependant and uses it as a template. Rifampin targets and inactivates the RNA polymerase bacterial enzyme. Rifampin works against staph infection and the Mycobacterium tuberculosis (TB). Staphylococcus aureus that is phagocytosed by the macrophages causes them to become intracellular (antibiotics cannot reach). 30S: 1.tetracyclines (doxycycline): avoided in children less than 12 years (impaired growth, and teeth discoloration) may be used to treat Lyme disease. 2.aminoglycosides (gentamycin): possible problems with ears or kidneys. It is used to treat ope fractures type III. 50S: 1.Clindamycin: may cause pseudomembranous colitis (c.diff). monitor patients who are taking warfarin (Coumadin). It can wipe out the bacteria flora from the gut (intestinal bacteria secrete vitamin K). usually used if the patient is allergic to penicillins or Ancef. Clindamycin creates C/diff that is helped by antibiotics. Use cirpo if allergy to clindamycin or flagyl if c.diff is created. Clindamycin will achieve the highest concentration in bone. 2.macrolides (erythromycin): be aware of Coumadin interaction. 3.Zyvox (linezolid): used in resistant gram-positive bacteria 4.chloramphenicol: watch out for anaplastic anemia. Other points of interest •When you add antibiotics to the cement, the maximum effect occurs at 2 weeks and there will be no effect at 8 weeks. •Panton-Valentine Leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus and this toxin may cause necrotizing fasciitis or necrosis of the tissues. It is usually found in the community-acquired cases of MRSA. There will be more complex infection. More incidence of DVT and PE. Become a friend on facebook: http://www.facebook.com/drebraheim Follow me on twitter: https://twitter.com/#!/DrEbraheim_UTMC Donate to the University of Toledo Foundation Department of Orthopaedic Surgery Endowed Chair Fund: https://www.utfoundation.org/foundation/home/Give_Online.aspx?sig=29
Просмотров: 7748 nabil ebraheim
5 Antibiotics Declared Safe At All Stages of Pregnancy.
5 Antibiotics Declared Safe At All Stages of Pregnancy.... ►►https://youtu.be/fCziSMPMjdM Once that plus sign appears on your pregnancy test, you know your body is in for a lot of changes. But what you probably didn't know is that those changes can mean more infections -- and more antibiotics. The most recent National Birth Defects Prevention Study of more than 13,000 pregnant women found that about 30 percent of women undergo at least one course of antibiotic treatment between the three months prior to conception and the end of their pregnancies, most commonly during the fourth month of pregnancy. Select antibiotic use has the potential to cause congenital abnormalities in newborns. So do you take the antibiotic and get better, or skip it and risk birth defects? Don't worry -- according to the study, it's not that black-and-white and there are safe options available. Here, we provide tips on keeping both you and your baby healthy.
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Alergic Reaction to Penicillin
I discovered the hard way that I'm alergic to Penicillin. Check out the effects.
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Is cephalexin a form of penicillin
Is cephalexin a form of penicillin - Find out more explanation for : 'Is cephalexin a form of penicillin' only from this channel. Information Source: google
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Is Keflex a form of penicillin
Is Keflex a form of penicillin - Find out more explanation for : 'Is Keflex a form of penicillin' only from this channel. Information Source: google
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Ampicillin Nursing Considerations, Side Effects and Mechanism of Action Pharmacology for Nurses
Grab our free cheatsheet covering the 50 most commonly prescribed medications right here: http://www.nrsng.com/50meds View full post: https://www.nrsng.com/ampicillin-principen/ Listen to all the episodes at: https://www.nrsng.com/medmaster-podcast/ Ampicillin Generic Name: ampicillin Trade Name: Principen Indication: skin infections, soft tissue infections, otitis media, sinusitis, respiratory infections, GU infections, meningitis, septicemia Action: bactericidal, broader spectrum than penicillin, binds to cell wall leading to bacterial cell death Therapeutic Class: anti-infective Pharmacologic Class: aminopenicillin Nursing Considerations  contraindicated in penicillin allergy, use caution in renal insufficiency  may lead to seizures, diarrhea, anaphylaxes, super infection  assess for infection  monitor liver function tests  instruct patient on signs of super infection: fury over growth on tongue, vaginal itching, loose and foul smelling stool  pt should not use with oral contraceptive use.
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Sulfonamides and Penicillins
1. Differentiate between bactericidal and bacteriostatic. 2. Define the term "broad spectrum antibiotic and explain why it might be used. 3. Define the term "narrow spectrum antibiotic and explain why it might be used. 4. List indications and contraindications for the use of sulfonamides. 5. Discuss why combination therapy is common when using sulfonamides. 6. List the five main groups of penicillins and give an instance when each might be most effective. Product ID: CLP113 Year: 2011, 2010 Duration: 17 minutes Other Programs Included in this Series: Assessment of an Infection Nursing Implications Cephalosporin, Aminoglycosides, Macrolides & Quinolones Antifungal and Antiviral Agents Antitubercular Agents Please contact HEAT Inc., to purchase the full video sales@heatinc.ca or info@heatinc.ca Please visit our website at www.heatinc.ca
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Penicillin in Medicine and Surgery 220581-04.mp4 | Footage Farm
Penicillin in Medicine and Surgery Pt. 1 of 3 Presented by H. Sidney Newcomer, M.D. Medical director E.R. Squibb & sons. New York Bust of Louis Pasteur. Reconstruction in laboratory of Alexander Fleming discovery of penicillin. Pages of journal re penicillin - still of professor Florey. Vial containing penicillin - laboratory procedures. Construction work on factory. Mass production line. Fermentation tanks for penicillin. Graph showing production of concentrated penicillin. Laboratory procedures - scientific testing. Penicillin into vials - frozen. Now ready for use. Small boxes off production line. Dr Harrison Flippen ? at desk speaks re knowledge and use of penicillin. Swab / smear test of organisms. Microscope shots of organisms. Cutaway model of human body showing internal organs. Cutaway of head showing brain & skull. CU healed over infected abscess on man head. Doctor & nurse w/ medicine trolley visit male patient in ward. Different doctor taking blood from patient. Penicillin prepared in syringe & injected by nurse. Oral / tablets of penicillin. Man in hospital bed given breakfast by nurse. Man feeling better sits in chair reading. Doctors & nurses round bed in isolation ward. Patient examined. Graph re dosage. See also parts 2 & 3 If you wish to order high quality material of this film, or want to know more about our collection, contact us at info@footagefarm.co.uk
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Anaphylactic Shock: Symptoms, Causes, and Treatment
Like, Comment, Subscribe and invite all your friends to see our videos. https://www.youtube.com/channel/UCfR3Y90G-fFDYI6i7E7xPBQ What is anaphylactic shock? When exposed to something they’re allergic to, some people experience a potentially life-threatening reaction called anaphylaxis. As a result, their immune system releases chemicals that flood the body. This can lead to anaphylactic shock. When your body goes into anaphylactic shock, your blood pressure suddenly drops and your airways narrow, possibly blocking normal breathing. This condition is dangerous. If it isn’t treated immediately, it can result in serious complications and even be fatal. What are the symptoms of anaphylactic shock? You will experience symptoms of anaphylaxis before anaphylactic shock sets in. These symptoms shouldn’t be ignored. They include: skin reactions such as hives, flushed skin, or pale skin suddenly feeling too warm feeling like you have a lump in your throat or difficulty swallowing nausea, vomiting, or diarrhea abdominal pain a weak and rapid pulse runny nose and sneezing swollen tongue or lips wheezing or difficulty breathing a sense that something is wrong with your body tingling hands, feet, mouth, or scalp If you think you’re experiencing anaphylaxis, seek medical attention immediately. You should also be aware of the symptoms of anaphylactic shock. These symptoms include: struggling to breathe dizziness confusion sudden feeling of weakness loss of consciousness What are the causes and risk factors of anaphylaxis? Anaphylaxis is caused by an overreaction of your immune system to an allergen, or something your body is allergic to. In turn, anaphylaxis can result in anaphylactic shock. Common triggers for anaphylaxis include: certain medications such as penicillin insect stings foods such as tree nuts, shellfish, milk, and eggs agents used in immunotherapy latex In rare cases, exercise and aerobic activity such as running can trigger anaphylaxis. Sometimes a cause for this reaction is never identified. This type of anaphylaxis is called idiopathic. If you aren’t sure what’s triggering your allergy attacks, your doctor may order an allergy test to look for what’s causing them. Risk factors for severe anaphylaxis and anaphylactic shock include: a previous anaphylactic reaction allergies or asthma a family history of anaphylaxis How is anaphylactic shock treated? The first step for treating anaphylactic shock will likely be injecting epinephrine (adrenaline) immediately. This can reduce the severity of the allergic reaction. At the hospital, you may receive cortisone and antihistamines intravenously. These help reduce inflammation in the air passages, improving the ability to breathe. Your doctor may give you beta-agonists such as albuterol to make breathing easier. You may also receive supplemental oxygen to help your body get the oxygen it needs. Any complications you’ve developed as a result of anaphylactic shock will also be treated. {The information provided on this channel and its videos is for general purposes only and should not be considered as professional advice. We are trying to provide a perfect, valid, specific, detailed information. we are not a licensed professional so make sure with your professional consultant in case you need}.
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rant-can we have a REAL discussion about fish antibiotics?1
"The principal consequence of deterioration is a reduction of therapeutic activity, which leads to more or less grave consequences for the individual and/or community. For example, the use of expired antibacterials does not cure an infection and also favours the emergence of resistant strains. It is not recommended to compensate for a possible reduction of activity by a random increase in the usual dose, as there is a real danger of overdose when using toxic drugs. In time, certain drugs undergo a deterioration leading to the development of substances much more dangerous, thus an increase in toxicity. Tetracycline is the principal example: the pale, yellow powder becomes brownish and viscous, its use therefore being dangerous even if before the expiry date. An increase in allergen strength has been observed in certain drugs such as penicillins and cephalosporins." http://refbooks.msf.org/msf_docs/en/essential_drugs/ed_en.pdf http://thesurvivaldoctor.com/2015/07/21/fish-antibiotics-for-humans/ http://thesurvivaldoctor.com/2015/08/05/expired-antibiotics/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031442/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008927/ http://www.safetyandquality.gov.au/wp-content/uploads/2012/02/4.3-A-Quick-Guide-to-Switch_Southern-Health.pdf "These findings underscore the continued need for preventive strategies, as well as alternative improved diagnostic and treatment regimens. Clinical approaches for the management of childhood pneumonia are considerably hampered by the lack of a gold standard, as classic microbiological methods have poor sensitivity and current algorithms lack sufficient specificity. It is therefore likely that community strategies for the recognition and management of pneumonia by ancillary health workers that rely on simple clinical criteria, other than auscultation, will over diagnose bacterial pneumonia. There are legitimate concerns that widespread use of first‐line antibiotics for all ARIs will lead to loss of effectiveness. Table 1​1 summarises the outcomes from recent therapeutic trials for the treatment of non‐severe pneumonia, indicating treatment failure rates exceeding 15% in many cases. It is therefore imperative that antibiotic regimens for both dosage and duration be evidence based and their use restricted as much as possible. It is therefore important that developing countries look at a combination of strategies for reducing the burden and mortality from pneumonia. These include the important role of preventive strategies such as control of environmental factors (eg, indoor air pollution)15 dealing with prevalent micronutrient deficiencies such as zinc and vitamin A deficiencies and promotion of household behaviours such as exclusive breast feeding16,17 and hand washing.18 Many of these preventive strategies have health benefits that far exceed mere reduction in respiratory infections, such as reduction in diarrhoea burden and improvement in nutrition indices." http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2083673/ http://jid.oxfordjournals.org/content/183/Supplement_1/S1.full http://umm.edu/health/medical/reports/articles/travel-to-developing-countries "Analgesics and fluids are used for pain and dehydration, the limb is splinted for comfort andto prevent contractures and antibiotics are commenced empirically. Drugs can be changed when culture and sensitivity results become available. The duration and routes of antibiotic therapy have traditionally been 1 to 2 weeks intravenously followed by 3 to 6 weeks of oral therapy. Some literature suggest a shorter duration of therapy is efficacious.13 Generally however, sequential intravenous — oral therapy is the accepted standard. Appropriate intravenous therapy should be continued until there is clinical improvement and the CRP levels approach normal. Oral therapy is then commenced and continued until the ESR normalize" http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895795/ http://emedicine.medscape.com/article/237521-overview "- suprainhibitory blood levels of drug can be attained by those routes. -Infants and patients older than 60 years of age tend to have a higher gastric pH and thus may have impaired absorption of such agents. Chronically ill patients, including those with HIV infection, also are more likely than the general population to have achlorhydria -This section briefly reviews the results of a number of such studies in which oral administration was used to treat serious infections. Some studies began with iv therapy initially, changing to oral administration as soon as patients were feeling better, had stable vital signs, and were able to take nutrition" http://cid.oxfordjournals.org/content/24/3/457.full.pdf http://www.who.int/occupational_health/activities/5injvsora.pdf http://blogs.jwatch.org/hiv-id-observations/index.php/id-learning-unit-antibiotics-with-excellent-oral-absorption/2013/05/16/
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Cefuroxime Axetil Tablets Rectum 500 Fake Medicine B. No. R-095
Common Dosage for Cefuroxime Axetil The drug dosage and form is decided by the physician based upon: • Age and body weight of the patient • Health status/medical condition of the patient • Disease severity • Reaction to the first dose • History of allergy/drug reactions A typical adult dosage for pharyngitis, tonsillitis, sinusitis, bronchitis, skin structure infections is 250 mg twice daily and for more severe infections, e.g., Pneumonia – 500 mg twice daily. Cefuroxime Axetil tablets are not recommended for infants and children less than 12 years of age. Cefuroxime Axetil Suspensions – The dose depends on the weight of the child. Your doctor or pharmacist will tell you exactly how many teaspoonful or 5 mL measures of the liquid suspension your child must take. Precautions – When to Avoid Cefuroxime Axetil? • Cefuroxime Axetil doesn’t work in case of viral infections (such as flu, common cold)). Unnecessary use of antibiotic must be avoided because it decreases its efficacy. • Cefuroxime Axetil should be avoided in patients with previous allergic reactions to cefuroxime, cephalosporin, penicillin, or other drugs. • Aspartame present in Cefuroxime Axetil suspension is a source of phenylalanine and therefore it should not be used in patients suffering from phenylketonuria. • Cefuroxime Axetil should not be used in patients with a history of cephalosporin-associated hemolytic anaemia. • The use of Cefuroxime Axetil should be avoided in patients suffering from gastrointestinal disease, particularly colitis. • Cefuroxime Axetil should be avoided if you are having a urine test for sugar. False positive reactions may occur. • Cefuroxime Axetil should be avoided if you are diabetic. CEFTIN Suspension contains sugar (about 3 g/5 mL). • Cefuroxime Axetil should be avoided if you are pregnant or planning to become pregnant. • Cefuroxime Axetil should be avoided if you are breastfeeding or planning to breastfeed. Cefuroxime is excreted in human breast milk. Common side effects of cefuroxime Tablets Diarrhea, nausea, vomiting, loose stools. Reports of abdominal pain have occurred. • Clostridium Difficile-Associated Disease (CDAD) has been reported with use of many antibacterial agents including Cefuroxime Axetil. • Transient increases of liver enzyme levels [ALT, AST, LDH]. • Headache and dizziness • Allergic reactions – Rashes, itching, or shortness of breath may occur. • As with other cephalosporins, there have been rare reports of drug fever. Decreased hemoglobin, and very rarely a faster breakdown of red blood cells leading to a form of anemia (hemolytic anemia) with symptoms such as fatigue, shortness of breath and looking pale can occur. Additionally, drowsiness, infections in vagina and transient increases in serum bilirubin, creatinine, alkaline phosphatase, and urea nitrogen van occur as side-effects with injectable forms of Cefuroxime Axetil. Effects of Cefuroxime Axetil on Organs? • Effects on liver have been reported. Symptoms of liver damage include – o Jaundice (yellowing of the eyes and skin) o Pain in the stomach o Nausea o Vomiting o Fever o Severe tiredness o Dark urine o Increased levels of liver enzymes • In patients suffering from kidney diseases, the dosage of Cefuroxime Axetil should be decreased.
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Antibiotics - beta-lactams (penicillin).
First video of the functioning of the antibiotics. Betalactam antibiotics are a broad class of antibiotics including penicillin derivatives, cephalosporins, monobactams, carbacephems, carbapenems, and beta-lactamase inhibitors (β-lactamase); basically any antibiotic agent that contains a β-lactam ring in its molecular structure. They are the most widely used group among the antibiotics available.
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Cephalexin Challenge...... Conquered!?
Gabby had her Cephalexin challenge today, she did an amazing job even though she was scared to begin with. Follow us on Facebook - https://www.facebook.com/themarlers4/ Twitter - https://twitter.com/TheMarlers4 Video edited using CyberLink PowerDirector
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